2020-03-27 20:48:18 UTC

50 files changed, 145 insertions, 145 deletions

diff --git a/metadata/md5-cache/sci-chemistry/GromacsWrapper-0.8.0 b/metadata/md5-cache/sci-chemistry/GromacsWrapper-0.8.0
index b927700a9457..6e82f63a601c 100644
--- a/metadata/md5-cache/sci-chemistry/GromacsWrapper-0.8.0
+++ b/metadata/md5-cache/sci-chemistry/GromacsWrapper-0.8.0
@@ -1,4 +1,4 @@
-BDEPEND=dev-python/six[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/numpy[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/matplotlib[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] sci-libs/numkit[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] python_targets_python3_6? ( dev-lang/python:3.6 ) python_targets_python3_7? ( dev-lang/python:3.7 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)]
+BDEPEND=dev-python/six[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/numpy[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/matplotlib[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] sci-libs/numkit[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) python_targets_python3_7? ( >=dev-lang/python-3.7.6:3.7 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)]
 DEFINED_PHASES=compile configure install prepare test unpack
 DESCRIPTION=Python framework for Gromacs
 EAPI=7
@@ -6,9 +6,9 @@ HOMEPAGE=https://gromacswrapper.readthedocs.io
 IUSE=python_targets_python3_6 python_targets_python3_7
 KEYWORDS=~amd64 ~x86
 LICENSE=GPL-3 LGPL-3
-RDEPEND=python_targets_python3_6? ( dev-lang/python:3.6 ) python_targets_python3_7? ( dev-lang/python:3.7 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)]
+RDEPEND=python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) python_targets_python3_7? ( >=dev-lang/python-3.7.6:3.7 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)]
 REQUIRED_USE=|| ( python_targets_python3_6 python_targets_python3_7 )
 SLOT=0
 SRC_URI=https://github.com/Becksteinlab/GromacsWrapper/archive/release-0.8.0.tar.gz -> GromacsWrapper-0.8.0.tar.gz
-_eclasses_=distutils-r1	577e2308f7b36e26062d464f59a5ee6c	eutils	fcb2aa98e1948b835b5ae66ca52868c5	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-snapshot	b1abf460a493fc59ebb25de0df3f09dd
+_eclasses_=distutils-r1	577e2308f7b36e26062d464f59a5ee6c	eutils	fcb2aa98e1948b835b5ae66ca52868c5	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-snapshot	b1abf460a493fc59ebb25de0df3f09dd
 _md5_=72c468e398bd8beabcabfe9521714c2c
diff --git a/metadata/md5-cache/sci-chemistry/MDAnalysis-0.18.0-r1 b/metadata/md5-cache/sci-chemistry/MDAnalysis-0.18.0-r1
index 403a90b8d697..2119ec515a25 100644
--- a/metadata/md5-cache/sci-chemistry/MDAnalysis-0.18.0-r1
+++ b/metadata/md5-cache/sci-chemistry/MDAnalysis-0.18.0-r1
@@ -1,4 +1,4 @@
-BDEPEND=dev-python/numpy[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] sci-libs/scipy[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] sci-biology/biopython[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/networkx[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/GridDataFormats[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/netcdf4-python[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/mmtf-python[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/gsd[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/mock[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/duecredit[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] test? ( dev-python/nose[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] ) python_targets_python3_6? ( dev-lang/python:3.6 ) python_targets_python3_7? ( dev-lang/python:3.7 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)]
+BDEPEND=dev-python/numpy[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] sci-libs/scipy[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] sci-biology/biopython[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/networkx[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/GridDataFormats[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/netcdf4-python[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/mmtf-python[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/gsd[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/mock[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/duecredit[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] test? ( dev-python/nose[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] ) python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) python_targets_python3_7? ( >=dev-lang/python-3.7.6:3.7 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)]
 DEFINED_PHASES=compile configure install prepare test
 DESCRIPTION=A python library to analyze and manipulate molecular dynamics trajectories
 EAPI=7
@@ -6,10 +6,10 @@ HOMEPAGE=https://www.mdanalysis.org
 IUSE=test python_targets_python3_6 python_targets_python3_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=GPL-2
-RDEPEND=dev-python/numpy[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] sci-libs/scipy[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] sci-biology/biopython[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/networkx[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/GridDataFormats[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/netcdf4-python[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/mmtf-python[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/gsd[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/mock[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/duecredit[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] python_targets_python3_6? ( dev-lang/python:3.6 ) python_targets_python3_7? ( dev-lang/python:3.7 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)]
+RDEPEND=dev-python/numpy[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] sci-libs/scipy[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] sci-biology/biopython[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/networkx[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/GridDataFormats[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/netcdf4-python[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/mmtf-python[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/gsd[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/mock[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/duecredit[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) python_targets_python3_7? ( >=dev-lang/python-3.7.6:3.7 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)]
 REQUIRED_USE=|| ( python_targets_python3_6 python_targets_python3_7 )
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=mirror://pypi/M/MDAnalysis/MDAnalysis-0.18.0.tar.gz
-_eclasses_=distutils-r1	577e2308f7b36e26062d464f59a5ee6c	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
+_eclasses_=distutils-r1	577e2308f7b36e26062d464f59a5ee6c	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
 _md5_=f3070373659b2043aeeeeb07a35e203d
diff --git a/metadata/md5-cache/sci-chemistry/ParmEd-2.7.3 b/metadata/md5-cache/sci-chemistry/ParmEd-2.7.3
index 1825150a572f..b04ee0667d69 100644
--- a/metadata/md5-cache/sci-chemistry/ParmEd-2.7.3
+++ b/metadata/md5-cache/sci-chemistry/ParmEd-2.7.3
@@ -1,14 +1,14 @@
 DEFINED_PHASES=compile configure install prepare test unpack
-DEPEND=dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-libs/scipy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] python_targets_python3_6? ( dev-lang/python:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
+DEPEND=dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-libs/scipy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
 DESCRIPTION=Parameter/topology editor and molecular simulator
 EAPI=6
 HOMEPAGE=https://parmed.github.io/ParmEd/html/index.html
 IUSE=python_targets_python3_6
 KEYWORDS=~amd64 ~x86
 LICENSE=LGPL-2
-RDEPEND=dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-libs/scipy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] python_targets_python3_6? ( dev-lang/python:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
+RDEPEND=dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-libs/scipy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
 REQUIRED_USE=|| ( python_targets_python3_6 )
 SLOT=0
 SRC_URI=https://github.com/ParmEd/ParmEd/archive/2.7.3.tar.gz -> ParmEd-2.7.3.tar.gz
-_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	vcs-snapshot	b1abf460a493fc59ebb25de0df3f09dd	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	vcs-snapshot	b1abf460a493fc59ebb25de0df3f09dd	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=cdbdaf38c7805dc4b608e00a021ba743
diff --git a/metadata/md5-cache/sci-chemistry/ParmEd-3.0.3 b/metadata/md5-cache/sci-chemistry/ParmEd-3.0.3
index 60cdff133971..c51c3ca717ac 100644
--- a/metadata/md5-cache/sci-chemistry/ParmEd-3.0.3
+++ b/metadata/md5-cache/sci-chemistry/ParmEd-3.0.3
@@ -1,14 +1,14 @@
 DEFINED_PHASES=compile configure install prepare test unpack
-DEPEND=dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-libs/scipy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] python_targets_python3_6? ( dev-lang/python:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
+DEPEND=dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-libs/scipy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
 DESCRIPTION=Parameter/topology editor and molecular simulator
 EAPI=6
 HOMEPAGE=https://parmed.github.io/ParmEd/html/index.html
 IUSE=python_targets_python3_6
 KEYWORDS=~amd64 ~x86
 LICENSE=LGPL-2
-RDEPEND=dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-libs/scipy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] python_targets_python3_6? ( dev-lang/python:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
+RDEPEND=dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-libs/scipy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
 REQUIRED_USE=|| ( python_targets_python3_6 )
 SLOT=0
 SRC_URI=https://github.com/ParmEd/ParmEd/archive/3.0.3.tar.gz -> ParmEd-3.0.3.tar.gz
-_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	vcs-snapshot	b1abf460a493fc59ebb25de0df3f09dd	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	vcs-snapshot	b1abf460a493fc59ebb25de0df3f09dd	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=1759a2d24533dcf7076abeec2c3b78f2
diff --git a/metadata/md5-cache/sci-chemistry/apbs-1.4.1-r2 b/metadata/md5-cache/sci-chemistry/apbs-1.4.1-r2
index f733b9bac12a..7c01520e7d7c 100644
--- a/metadata/md5-cache/sci-chemistry/apbs-1.4.1-r2
+++ b/metadata/md5-cache/sci-chemistry/apbs-1.4.1-r2
@@ -1,14 +1,14 @@
 DEFINED_PHASES=compile configure install prepare setup test
-DEPEND=dev-cpp/eigen:3 dev-libs/maloc[mpi=] sys-libs/readline virtual/blas fetk? ( sci-libs/amd sci-libs/fetk sci-libs/superlu sci-libs/umfpack ) mpi? ( virtual/mpi ) python? ( python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) ) virtual/pkgconfig doc? ( app-doc/doxygen ) sys-devel/make >=dev-util/cmake-3.9.6 python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) python_single_target_python2_7? ( >=dev-python/setuptools-42.0.2[python_targets_python2_7(-)] )
+DEPEND=dev-cpp/eigen:3 dev-libs/maloc[mpi=] sys-libs/readline virtual/blas fetk? ( sci-libs/amd sci-libs/fetk sci-libs/superlu sci-libs/umfpack ) mpi? ( virtual/mpi ) python? ( python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) ) virtual/pkgconfig doc? ( app-doc/doxygen ) sys-devel/make >=dev-util/cmake-3.9.6 python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) python_single_target_python2_7? ( >=dev-python/setuptools-42.0.2[python_targets_python2_7(-)] )
 DESCRIPTION=Evaluation of electrostatic properties of nanoscale biomolecular systems
 EAPI=6
 HOMEPAGE=https://www.poissonboltzmann.org/apbs/
 IUSE=debug doc examples fast +fetk iapbs mpi openmp python tools +python_single_target_python2_7
 KEYWORDS=amd64 ppc x86 ~amd64-linux ~x86-linux
 LICENSE=BSD
-RDEPEND=dev-cpp/eigen:3 dev-libs/maloc[mpi=] sys-libs/readline virtual/blas fetk? ( sci-libs/amd sci-libs/fetk sci-libs/superlu sci-libs/umfpack ) mpi? ( virtual/mpi ) python? ( python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) ) python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] )
+RDEPEND=dev-cpp/eigen:3 dev-libs/maloc[mpi=] sys-libs/readline virtual/blas fetk? ( sci-libs/amd sci-libs/fetk sci-libs/superlu sci-libs/umfpack ) mpi? ( virtual/mpi ) python? ( python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) ) python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] )
 REQUIRED_USE=iapbs? ( fetk ) mpi? ( !python ) python? ( tools fetk iapbs ^^ ( python_single_target_python2_7 ) ) ^^ ( python_single_target_python2_7 )
 SLOT=0
 SRC_URI=https://github.com/Electrostatics/apbs-pdb2pqr/archive/74fcb8676de69ed04ddab8976a8b05a6caaf4d65.zip -> apbs-1.4.1.zip
-_eclasses_=cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=f41a19855208ab285fe5f38b9cd915f0
diff --git a/metadata/md5-cache/sci-chemistry/autodock-4.2.6 b/metadata/md5-cache/sci-chemistry/autodock-4.2.6
index 242b4e78a369..a5c55c10ea38 100644
--- a/metadata/md5-cache/sci-chemistry/autodock-4.2.6
+++ b/metadata/md5-cache/sci-chemistry/autodock-4.2.6
@@ -1,5 +1,5 @@
 DEFINED_PHASES=compile configure install postinst prepare setup test
-DEPEND=test? ( || ( >=dev-lang/python-2.7.5-r2:2.7 ) ) >=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.1:1.16 >=sys-devel/automake-1.15.1:1.15 ) >=sys-devel/autoconf-2.69 >=sys-devel/libtool-2.4
+DEPEND=test? ( || ( >=dev-lang/python-2.7.17-r1:2.7 ) ) >=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.1:1.16 >=sys-devel/automake-1.15.1:1.15 ) >=sys-devel/autoconf-2.69 >=sys-devel/libtool-2.4
 DESCRIPTION=A suite of automated docking tools
 EAPI=5
 HOMEPAGE=http://autodock.scripps.edu/
@@ -9,5 +9,5 @@ LICENSE=GPL-2
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=http://autodock.scripps.edu/downloads/autodock-registration/tars/dist426/autodocksuite-4.2.6-src.tar.gz
-_eclasses_=autotools	7d999b62b8749fad43fff00620cedf47	desktop	3b1f1d9a6b749c9ce2d5182877265b23	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	libtool	f143db5a74ccd9ca28c1234deffede96	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	c26f95a5042de003dc58bef955e41c88	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	versionator	2352c3fc97241f6a02042773c8287748
+_eclasses_=autotools	7d999b62b8749fad43fff00620cedf47	desktop	3b1f1d9a6b749c9ce2d5182877265b23	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	libtool	f143db5a74ccd9ca28c1234deffede96	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	c26f95a5042de003dc58bef955e41c88	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	versionator	2352c3fc97241f6a02042773c8287748
 _md5_=1f9abcb2039d2207b2bd42046dc50467
diff --git a/metadata/md5-cache/sci-chemistry/bkchem-0.14.0_pre2-r2 b/metadata/md5-cache/sci-chemistry/bkchem-0.14.0_pre2-r2
index c712df992d54..f2d2ff7c520e 100644
--- a/metadata/md5-cache/sci-chemistry/bkchem-0.14.0_pre2-r2
+++ b/metadata/md5-cache/sci-chemistry/bkchem-0.14.0_pre2-r2
@@ -1,14 +1,14 @@
 DEFINED_PHASES=compile configure install prepare test
-DEPEND=cairo? ( dev-python/pycairo[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] ) python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7[tk] ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] >=dev-python/setuptools-42.0.2[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+DEPEND=cairo? ( dev-python/pycairo[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] ) python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7[tk] ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] >=dev-python/setuptools-42.0.2[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 DESCRIPTION=Chemical drawing program
 EAPI=5
 HOMEPAGE=http://bkchem.zirael.org/
 IUSE=cairo python_targets_python2_7
 KEYWORDS=~amd64 ~x86
 LICENSE=GPL-2
-RDEPEND=cairo? ( dev-python/pycairo[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] ) python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7[tk] ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+RDEPEND=cairo? ( dev-python/pycairo[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] ) python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7[tk] ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 REQUIRED_USE=|| ( python_targets_python2_7 )
 SLOT=0
 SRC_URI=http://bkchem.zirael.org/download/bkchem-0.14.0-pre2.tar.gz
-_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	versionator	2352c3fc97241f6a02042773c8287748	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	versionator	2352c3fc97241f6a02042773c8287748	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=f1633240a6e979c6aa07d3004b8f8a09
diff --git a/metadata/md5-cache/sci-chemistry/chemex-0.6.1-r3 b/metadata/md5-cache/sci-chemistry/chemex-0.6.1-r3
index b602a34b1373..548a35ad27dc 100644
--- a/metadata/md5-cache/sci-chemistry/chemex-0.6.1-r3
+++ b/metadata/md5-cache/sci-chemistry/chemex-0.6.1-r3
@@ -1,14 +1,14 @@
 DEFINED_PHASES=compile configure install prepare setup test
-DEPEND=python_single_target_python2_7? ( || ( >=dev-python/matplotlib-python2-1.1[python_targets_python2_7(-)] >=dev-python/matplotlib-1.1[python_targets_python2_7(-)] ) || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) || ( >=sci-libs/scipy-python2-0.11[python_targets_python2_7(-)] >=sci-libs/scipy-0.11[python_targets_python2_7(-)] ) ) python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) python_single_target_python2_7? ( >=dev-python/setuptools-42.0.2[python_targets_python2_7(-)] )
+DEPEND=python_single_target_python2_7? ( || ( >=dev-python/matplotlib-python2-1.1[python_targets_python2_7(-)] >=dev-python/matplotlib-1.1[python_targets_python2_7(-)] ) || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) || ( >=sci-libs/scipy-python2-0.11[python_targets_python2_7(-)] >=sci-libs/scipy-0.11[python_targets_python2_7(-)] ) ) python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) python_single_target_python2_7? ( >=dev-python/setuptools-42.0.2[python_targets_python2_7(-)] )
 DESCRIPTION=Program to fit chemical exchange induced shift and relaxation data
 EAPI=6
 HOMEPAGE=https://github.com/gbouvignies/chemex
 IUSE=+python_single_target_python2_7
 KEYWORDS=~amd64
 LICENSE=BSD
-RDEPEND=python_single_target_python2_7? ( || ( >=dev-python/matplotlib-python2-1.1[python_targets_python2_7(-)] >=dev-python/matplotlib-1.1[python_targets_python2_7(-)] ) || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) || ( >=sci-libs/scipy-python2-0.11[python_targets_python2_7(-)] >=sci-libs/scipy-0.11[python_targets_python2_7(-)] ) ) python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] )
+RDEPEND=python_single_target_python2_7? ( || ( >=dev-python/matplotlib-python2-1.1[python_targets_python2_7(-)] >=dev-python/matplotlib-1.1[python_targets_python2_7(-)] ) || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) || ( >=sci-libs/scipy-python2-0.11[python_targets_python2_7(-)] >=sci-libs/scipy-0.11[python_targets_python2_7(-)] ) ) python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] )
 REQUIRED_USE=^^ ( python_single_target_python2_7 )
 SLOT=0
 SRC_URI=https://github.com/gbouvignies/chemex/archive/0.6.1.tar.gz -> chemex-0.6.1.tar.gz
-_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=e8175331c954b599362e293b84ccf39c
diff --git a/metadata/md5-cache/sci-chemistry/eden-5.3-r2 b/metadata/md5-cache/sci-chemistry/eden-5.3-r2
index afad4011d4f1..669ceaf8bed5 100644
--- a/metadata/md5-cache/sci-chemistry/eden-5.3-r2
+++ b/metadata/md5-cache/sci-chemistry/eden-5.3-r2
@@ -1,14 +1,14 @@
 DEFINED_PHASES=compile install prepare setup
-DEPEND=sci-libs/fftw:2.1 sci-libs/gsl python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] virtual/pkgconfig
+DEPEND=sci-libs/fftw:2.1 sci-libs/gsl python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] virtual/pkgconfig
 DESCRIPTION=A crystallographic real-space electron-density refinement & optimization program
 EAPI=5
 HOMEPAGE=http://www.gromacs.org/pipermail/eden-users/
 IUSE=double-precision python_targets_python2_7
 KEYWORDS=amd64 x86
 LICENSE=GPL-2
-RDEPEND=sci-libs/fftw:2.1 sci-libs/gsl python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+RDEPEND=sci-libs/fftw:2.1 sci-libs/gsl python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 REQUIRED_USE=|| ( python_targets_python2_7 )
 SLOT=0
 SRC_URI=mirror://gentoo/eden_V5.3.tar.gz
-_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
+_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
 _md5_=595d21c1540fa3217d4dc5e435b47495
diff --git a/metadata/md5-cache/sci-chemistry/freeon-1.0.10 b/metadata/md5-cache/sci-chemistry/freeon-1.0.10
index 0fc7edb4e172..c36a0ab2f273 100644
--- a/metadata/md5-cache/sci-chemistry/freeon-1.0.10
+++ b/metadata/md5-cache/sci-chemistry/freeon-1.0.10
@@ -1,5 +1,5 @@
 DEFINED_PHASES=prepare setup
-DEPEND=sci-libs/hdf5 virtual/blas virtual/lapack || ( dev-lang/python:3.6 ) >=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.1:1.16 >=sys-devel/automake-1.15.1:1.15 ) >=sys-devel/autoconf-2.69 >=sys-devel/libtool-2.4 virtual/fortran
+DEPEND=sci-libs/hdf5 virtual/blas virtual/lapack || ( >=dev-lang/python-3.6.10:3.6 ) >=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.1:1.16 >=sys-devel/automake-1.15.1:1.15 ) >=sys-devel/autoconf-2.69 >=sys-devel/libtool-2.4 virtual/fortran
 DESCRIPTION=An experimental suite of programs for linear scaling quantum chemistry
 EAPI=6
 HOMEPAGE=http://www.freeon.org
@@ -8,5 +8,5 @@ LICENSE=GPL-3
 RDEPEND=sci-libs/hdf5 virtual/blas virtual/lapack virtual/fortran
 SLOT=0
 SRC_URI=http://download.savannah.gnu.org/releases/freeon/freeon-1.0.10.tar.bz2
-_eclasses_=autotools	7d999b62b8749fad43fff00620cedf47	desktop	3b1f1d9a6b749c9ce2d5182877265b23	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	fortran-2	1a8c9d0b2d30f756bae6be4e9b39e46b	libtool	f143db5a74ccd9ca28c1234deffede96	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	c26f95a5042de003dc58bef955e41c88	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
+_eclasses_=autotools	7d999b62b8749fad43fff00620cedf47	desktop	3b1f1d9a6b749c9ce2d5182877265b23	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	fortran-2	1a8c9d0b2d30f756bae6be4e9b39e46b	libtool	f143db5a74ccd9ca28c1234deffede96	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	c26f95a5042de003dc58bef955e41c88	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
 _md5_=543485c2307080eeae76ca9260fb947b
diff --git a/metadata/md5-cache/sci-chemistry/freeon-1.0.8-r1 b/metadata/md5-cache/sci-chemistry/freeon-1.0.8-r1
index 414e4cbacc55..0d17d49bedab 100644
--- a/metadata/md5-cache/sci-chemistry/freeon-1.0.8-r1
+++ b/metadata/md5-cache/sci-chemistry/freeon-1.0.8-r1
@@ -1,5 +1,5 @@
 DEFINED_PHASES=compile configure install prepare setup test
-DEPEND=sci-libs/hdf5 virtual/blas virtual/lapack || ( >=dev-lang/python-2.7.5-r2:2.7 ) >=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.1:1.16 >=sys-devel/automake-1.15.1:1.15 ) >=sys-devel/autoconf-2.69 >=sys-devel/libtool-2.4 virtual/fortran
+DEPEND=sci-libs/hdf5 virtual/blas virtual/lapack || ( >=dev-lang/python-2.7.17-r1:2.7 ) >=app-portage/elt-patches-20170815 || ( >=sys-devel/automake-1.16.1:1.16 >=sys-devel/automake-1.15.1:1.15 ) >=sys-devel/autoconf-2.69 >=sys-devel/libtool-2.4 virtual/fortran
 DESCRIPTION=An experimental suite of programs for linear scaling quantum chemistry
 EAPI=5
 HOMEPAGE=http://www.freeon.org
@@ -8,5 +8,5 @@ LICENSE=GPL-3
 RDEPEND=sci-libs/hdf5 virtual/blas virtual/lapack virtual/fortran
 SLOT=0
 SRC_URI=http://download.savannah.gnu.org/releases/freeon/freeon-1.0.8.tar.bz2
-_eclasses_=autotools	7d999b62b8749fad43fff00620cedf47	autotools-utils	95db0904ad0f62535e18e5ccb67cce5e	desktop	3b1f1d9a6b749c9ce2d5182877265b23	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	fortran-2	1a8c9d0b2d30f756bae6be4e9b39e46b	libtool	f143db5a74ccd9ca28c1234deffede96	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	c26f95a5042de003dc58bef955e41c88	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
+_eclasses_=autotools	7d999b62b8749fad43fff00620cedf47	autotools-utils	95db0904ad0f62535e18e5ccb67cce5e	desktop	3b1f1d9a6b749c9ce2d5182877265b23	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	fortran-2	1a8c9d0b2d30f756bae6be4e9b39e46b	libtool	f143db5a74ccd9ca28c1234deffede96	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-any-r1	c26f95a5042de003dc58bef955e41c88	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
 _md5_=bd7229f9f40cac132fea1417b74adc9e
diff --git a/metadata/md5-cache/sci-chemistry/gmxapi-0.0.7.1 b/metadata/md5-cache/sci-chemistry/gmxapi-0.0.7.1
index f6d53ac8960e..60407c1b11a8 100644
--- a/metadata/md5-cache/sci-chemistry/gmxapi-0.0.7.1
+++ b/metadata/md5-cache/sci-chemistry/gmxapi-0.0.7.1
@@ -1,15 +1,15 @@
 BDEPEND=dev-util/ninja >=dev-util/cmake-3.9.6
 DEFINED_PHASES=compile configure install prepare test
-DEPEND=python_targets_python3_6? ( dev-lang/python:3.6 ) python_targets_python3_7? ( dev-lang/python:3.7 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] >=sci-chemistry/gromacs-2019:=
+DEPEND=python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) python_targets_python3_7? ( >=dev-lang/python-3.7.6:3.7 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] >=sci-chemistry/gromacs-2019:=
 DESCRIPTION=Gromacs API bindings
 EAPI=7
 HOMEPAGE=https://github.com/kassonlab/gmxapi
 IUSE=python_targets_python3_6 python_targets_python3_7
 KEYWORDS=~amd64 ~x86
 LICENSE=LGPL-2.1
-RDEPEND=python_targets_python3_6? ( dev-lang/python:3.6 ) python_targets_python3_7? ( dev-lang/python:3.7 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] >=sci-chemistry/gromacs-2019:= sci-libs/scikits[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/networkx[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)]
+RDEPEND=python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) python_targets_python3_7? ( >=dev-lang/python-3.7.6:3.7 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] >=sci-chemistry/gromacs-2019:= sci-libs/scikits[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/networkx[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)]
 REQUIRED_USE=|| ( python_targets_python3_6 python_targets_python3_7 )
 SLOT=0
 SRC_URI=https://github.com/kassonlab/gmxapi/archive/v0.0.7.1.tar.gz -> gmxapi-0.0.7.1.tar.gz
-_eclasses_=cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=f3cab1a66b71373c8f805ba35c74d750
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2019.5-r1 b/metadata/md5-cache/sci-chemistry/gromacs-2019.5-r1
index 506e5adcd535..9253765ab648 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2019.5-r1
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2019.5-r1
@@ -1,4 +1,4 @@
-BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) virtual/pkgconfig doc? ( app-doc/doxygen python_single_target_python2_7? ( dev-python/sphinx[python_targets_python2_7(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) dev-util/ninja >=dev-util/cmake-3.9.6
+BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) virtual/pkgconfig doc? ( app-doc/doxygen python_single_target_python2_7? ( dev-python/sphinx[python_targets_python2_7(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) dev-util/ninja >=dev-util/cmake-3.9.6
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=7
@@ -6,10 +6,10 @@ HOMEPAGE=http://www.gromacs.org/
 IUSE=X blas cuda +doc -double-precision +fftw +gmxapi +hwloc lapack +lmfit mkl mpi +offensive opencl openmp +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 +python_single_target_python2_7
 KEYWORDS=amd64 arm x86 ~amd64-linux ~x86-linux ~x64-macos ~x86-macos
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
-RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] )
+RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] )
 REQUIRED_USE=|| ( single-precision double-precision ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python2_7 )
 RESTRICT=!test? ( test )
 SLOT=0/2019.5
 SRC_URI=ftp://ftp.gromacs.org/pub/gromacs/gromacs-2019.5.tar.gz test? ( http://gerrit.gromacs.org/download/regressiontests-2019.5.tar.gz )
-_eclasses_=bash-completion-r1	47a7402d95930413ce25ba8d857339bb	cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	cuda	bb861e5221b7272ac90c2f12791c1e66	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	readme.gentoo-r1	22ae82e140bdd95d17a34fd5fd733190	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=bash-completion-r1	47a7402d95930413ce25ba8d857339bb	cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	cuda	bb861e5221b7272ac90c2f12791c1e66	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	readme.gentoo-r1	22ae82e140bdd95d17a34fd5fd733190	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=cb6b16f5dce43e3eb029b767e41aa242
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2019.6 b/metadata/md5-cache/sci-chemistry/gromacs-2019.6
index b7a003d5ade3..6cc0b9366430 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2019.6
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2019.6
@@ -1,4 +1,4 @@
-BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) virtual/pkgconfig doc? ( app-doc/doxygen python_single_target_python2_7? ( dev-python/sphinx[python_targets_python2_7(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) dev-util/ninja >=dev-util/cmake-3.9.6
+BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) virtual/pkgconfig doc? ( app-doc/doxygen python_single_target_python2_7? ( dev-python/sphinx[python_targets_python2_7(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) dev-util/ninja >=dev-util/cmake-3.9.6
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=7
@@ -6,10 +6,10 @@ HOMEPAGE=http://www.gromacs.org/
 IUSE=X blas cuda +doc -double-precision +fftw +gmxapi +hwloc lapack +lmfit mkl mpi +offensive opencl openmp +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 +python_single_target_python2_7
 KEYWORDS=~amd64 ~arm ~x86 ~amd64-linux ~x86-linux ~x64-macos ~x86-macos
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
-RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] )
+RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] )
 REQUIRED_USE=|| ( single-precision double-precision ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python2_7 )
 RESTRICT=!test? ( test )
 SLOT=0/2019.6
 SRC_URI=ftp://ftp.gromacs.org/pub/gromacs/gromacs-2019.6.tar.gz test? ( http://gerrit.gromacs.org/download/regressiontests-2019.6.tar.gz )
-_eclasses_=bash-completion-r1	47a7402d95930413ce25ba8d857339bb	cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	cuda	bb861e5221b7272ac90c2f12791c1e66	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	readme.gentoo-r1	22ae82e140bdd95d17a34fd5fd733190	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=bash-completion-r1	47a7402d95930413ce25ba8d857339bb	cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	cuda	bb861e5221b7272ac90c2f12791c1e66	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	readme.gentoo-r1	22ae82e140bdd95d17a34fd5fd733190	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=ae608551e7776c6a014686d95e8a4a5d
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2019.9999 b/metadata/md5-cache/sci-chemistry/gromacs-2019.9999
index 668294453252..85c66afb3706 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2019.9999
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2019.9999
@@ -1,4 +1,4 @@
-BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) virtual/pkgconfig doc? ( app-doc/doxygen python_single_target_python2_7? ( dev-python/sphinx[python_targets_python2_7(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) dev-util/ninja >=dev-util/cmake-3.9.6 >=dev-vcs/git-1.8.2.1[curl]
+BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) virtual/pkgconfig doc? ( app-doc/doxygen python_single_target_python2_7? ( dev-python/sphinx[python_targets_python2_7(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) dev-util/ninja >=dev-util/cmake-3.9.6 >=dev-vcs/git-1.8.2.1[curl]
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=7
@@ -6,9 +6,9 @@ HOMEPAGE=http://www.gromacs.org/
 IUSE=X blas cuda +doc -double-precision +fftw +gmxapi +hwloc lapack +lmfit mkl mpi +offensive opencl openmp +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 +python_single_target_python2_7
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
 PROPERTIES=live
-RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] )
+RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] )
 REQUIRED_USE=|| ( single-precision double-precision ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python2_7 )
 RESTRICT=!test? ( test )
 SLOT=0/2019.9999
-_eclasses_=bash-completion-r1	47a7402d95930413ce25ba8d857339bb	cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	cuda	bb861e5221b7272ac90c2f12791c1e66	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	git-r3	86a0188f2ad9eb3d65e4d031ab8a0422	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	readme.gentoo-r1	22ae82e140bdd95d17a34fd5fd733190	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=bash-completion-r1	47a7402d95930413ce25ba8d857339bb	cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	cuda	bb861e5221b7272ac90c2f12791c1e66	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	git-r3	86a0188f2ad9eb3d65e4d031ab8a0422	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	readme.gentoo-r1	22ae82e140bdd95d17a34fd5fd733190	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=074cc86cc9733be5cadd37bc659b3ffe
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2020-r1 b/metadata/md5-cache/sci-chemistry/gromacs-2020-r1
index efab2f3c841a..c68194889215 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2020-r1
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2020-r1
@@ -1,4 +1,4 @@
-BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_6? ( dev-lang/python:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( dev-lang/python:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] ) !sci-chemistry/gmxapi virtual/pkgconfig doc? ( app-doc/doxygen python_single_target_python3_6? ( dev-python/sphinx[python_targets_python3_6(-)] ) python_single_target_python3_7? ( dev-python/sphinx[python_targets_python3_7(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) dev-util/ninja >=dev-util/cmake-3.9.6 python_single_target_python3_6? ( dev-lang/python:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( dev-lang/python:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] ) python_single_target_python3_6? ( >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)] ) python_single_target_python3_7? ( >=dev-python/setuptools-42.0.2[python_targets_python3_7(-)] )
+BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_6? ( >=dev-lang/python-3.6.10:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( >=dev-lang/python-3.7.6:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] ) !sci-chemistry/gmxapi virtual/pkgconfig doc? ( app-doc/doxygen python_single_target_python3_6? ( dev-python/sphinx[python_targets_python3_6(-)] ) python_single_target_python3_7? ( dev-python/sphinx[python_targets_python3_7(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) dev-util/ninja >=dev-util/cmake-3.9.6 python_single_target_python3_6? ( >=dev-lang/python-3.6.10:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( >=dev-lang/python-3.7.6:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] ) python_single_target_python3_6? ( >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)] ) python_single_target_python3_7? ( >=dev-python/setuptools-42.0.2[python_targets_python3_7(-)] )
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=7
@@ -6,10 +6,10 @@ HOMEPAGE=http://www.gromacs.org/
 IUSE=X blas cuda +doc -double-precision +fftw +gmxapi +gmxapi-legacy +hwloc lapack +lmfit mkl mpi +offensive opencl openmp +python +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 python_single_target_python3_6 python_single_target_python3_7
 KEYWORDS=~amd64 ~arm ~x86 ~amd64-linux ~x86-linux ~x64-macos ~x86-macos
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
-RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_6? ( dev-lang/python:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( dev-lang/python:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] ) !sci-chemistry/gmxapi python_single_target_python3_6? ( dev-lang/python:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( dev-lang/python:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] )
+RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_6? ( >=dev-lang/python-3.6.10:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( >=dev-lang/python-3.7.6:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] ) !sci-chemistry/gmxapi python_single_target_python3_6? ( >=dev-lang/python-3.6.10:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( >=dev-lang/python-3.7.6:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] )
 REQUIRED_USE=|| ( single-precision double-precision ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_6 python_single_target_python3_7 ) ^^ ( python_single_target_python3_6 python_single_target_python3_7 )
 RESTRICT=!test? ( test )
 SLOT=0/2020
 SRC_URI=ftp://ftp.gromacs.org/pub/gromacs/gromacs-2020.tar.gz test? ( http://gerrit.gromacs.org/download/regressiontests-2020.tar.gz )
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+_eclasses_=bash-completion-r1	47a7402d95930413ce25ba8d857339bb	cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	cuda	bb861e5221b7272ac90c2f12791c1e66	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	readme.gentoo-r1	22ae82e140bdd95d17a34fd5fd733190	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=08fcb4307b3e8090369aeb0809b6ab40
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2020.1 b/metadata/md5-cache/sci-chemistry/gromacs-2020.1
index 56022eb06274..49016569fc44 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2020.1
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2020.1
@@ -1,4 +1,4 @@
-BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_6? ( dev-lang/python:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( dev-lang/python:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] ) !sci-chemistry/gmxapi virtual/pkgconfig doc? ( app-doc/doxygen python_single_target_python3_6? ( dev-python/sphinx[python_targets_python3_6(-)] ) python_single_target_python3_7? ( dev-python/sphinx[python_targets_python3_7(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) dev-util/ninja >=dev-util/cmake-3.9.6 python_single_target_python3_6? ( dev-lang/python:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( dev-lang/python:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] ) python_single_target_python3_6? ( >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)] ) python_single_target_python3_7? ( >=dev-python/setuptools-42.0.2[python_targets_python3_7(-)] )
+BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_6? ( >=dev-lang/python-3.6.10:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( >=dev-lang/python-3.7.6:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] ) !sci-chemistry/gmxapi virtual/pkgconfig doc? ( app-doc/doxygen python_single_target_python3_6? ( dev-python/sphinx[python_targets_python3_6(-)] ) python_single_target_python3_7? ( dev-python/sphinx[python_targets_python3_7(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) dev-util/ninja >=dev-util/cmake-3.9.6 python_single_target_python3_6? ( >=dev-lang/python-3.6.10:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( >=dev-lang/python-3.7.6:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] ) python_single_target_python3_6? ( >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)] ) python_single_target_python3_7? ( >=dev-python/setuptools-42.0.2[python_targets_python3_7(-)] )
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=7
@@ -6,10 +6,10 @@ HOMEPAGE=http://www.gromacs.org/
 IUSE=X blas cuda +doc -double-precision +fftw +gmxapi +gmxapi-legacy +hwloc lapack +lmfit mkl mpi +offensive opencl openmp +python +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 python_single_target_python3_6 python_single_target_python3_7
 KEYWORDS=~amd64 ~arm ~x86 ~amd64-linux ~x86-linux ~x64-macos ~x86-macos
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
-RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_6? ( dev-lang/python:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( dev-lang/python:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] ) !sci-chemistry/gmxapi python_single_target_python3_6? ( dev-lang/python:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( dev-lang/python:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] )
+RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_6? ( >=dev-lang/python-3.6.10:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( >=dev-lang/python-3.7.6:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] ) !sci-chemistry/gmxapi python_single_target_python3_6? ( >=dev-lang/python-3.6.10:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( >=dev-lang/python-3.7.6:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] )
 REQUIRED_USE=|| ( single-precision double-precision ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_6 python_single_target_python3_7 ) ^^ ( python_single_target_python3_6 python_single_target_python3_7 )
 RESTRICT=!test? ( test )
 SLOT=0/2020.1
 SRC_URI=ftp://ftp.gromacs.org/pub/gromacs/gromacs-2020.1.tar.gz test? ( http://gerrit.gromacs.org/download/regressiontests-2020.1.tar.gz )
-_eclasses_=bash-completion-r1	47a7402d95930413ce25ba8d857339bb	cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	cuda	bb861e5221b7272ac90c2f12791c1e66	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	readme.gentoo-r1	22ae82e140bdd95d17a34fd5fd733190	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=bash-completion-r1	47a7402d95930413ce25ba8d857339bb	cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	cuda	bb861e5221b7272ac90c2f12791c1e66	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	readme.gentoo-r1	22ae82e140bdd95d17a34fd5fd733190	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=08fcb4307b3e8090369aeb0809b6ab40
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-2020.9999 b/metadata/md5-cache/sci-chemistry/gromacs-2020.9999
index 4decafb65c15..5f80f796aa8e 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-2020.9999
+++ b/metadata/md5-cache/sci-chemistry/gromacs-2020.9999
@@ -1,4 +1,4 @@
-BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_6? ( dev-lang/python:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( dev-lang/python:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] ) !sci-chemistry/gmxapi virtual/pkgconfig doc? ( app-doc/doxygen python_single_target_python3_6? ( dev-python/sphinx[python_targets_python3_6(-)] ) python_single_target_python3_7? ( dev-python/sphinx[python_targets_python3_7(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) dev-util/ninja >=dev-util/cmake-3.9.6 python_single_target_python3_6? ( dev-lang/python:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( dev-lang/python:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] ) python_single_target_python3_6? ( >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)] ) python_single_target_python3_7? ( >=dev-python/setuptools-42.0.2[python_targets_python3_7(-)] ) >=dev-vcs/git-1.8.2.1[curl]
+BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_6? ( >=dev-lang/python-3.6.10:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( >=dev-lang/python-3.7.6:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] ) !sci-chemistry/gmxapi virtual/pkgconfig doc? ( app-doc/doxygen python_single_target_python3_6? ( dev-python/sphinx[python_targets_python3_6(-)] ) python_single_target_python3_7? ( dev-python/sphinx[python_targets_python3_7(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) dev-util/ninja >=dev-util/cmake-3.9.6 python_single_target_python3_6? ( >=dev-lang/python-3.6.10:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( >=dev-lang/python-3.7.6:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] ) python_single_target_python3_6? ( >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)] ) python_single_target_python3_7? ( >=dev-python/setuptools-42.0.2[python_targets_python3_7(-)] ) >=dev-vcs/git-1.8.2.1[curl]
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=7
@@ -6,9 +6,9 @@ HOMEPAGE=http://www.gromacs.org/
 IUSE=X blas cuda +doc -double-precision +fftw +gmxapi +gmxapi-legacy +hwloc lapack +lmfit mkl mpi +offensive opencl openmp +python +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 python_single_target_python3_6 python_single_target_python3_7
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
 PROPERTIES=live
-RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_6? ( dev-lang/python:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( dev-lang/python:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] ) !sci-chemistry/gmxapi python_single_target_python3_6? ( dev-lang/python:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( dev-lang/python:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] )
+RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_6? ( >=dev-lang/python-3.6.10:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( >=dev-lang/python-3.7.6:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] ) !sci-chemistry/gmxapi python_single_target_python3_6? ( >=dev-lang/python-3.6.10:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( >=dev-lang/python-3.7.6:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] )
 REQUIRED_USE=|| ( single-precision double-precision ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_6 python_single_target_python3_7 ) ^^ ( python_single_target_python3_6 python_single_target_python3_7 )
 RESTRICT=!test? ( test )
 SLOT=0/2020.9999
-_eclasses_=bash-completion-r1	47a7402d95930413ce25ba8d857339bb	cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	cuda	bb861e5221b7272ac90c2f12791c1e66	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	git-r3	86a0188f2ad9eb3d65e4d031ab8a0422	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	readme.gentoo-r1	22ae82e140bdd95d17a34fd5fd733190	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=bash-completion-r1	47a7402d95930413ce25ba8d857339bb	cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	cuda	bb861e5221b7272ac90c2f12791c1e66	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	git-r3	86a0188f2ad9eb3d65e4d031ab8a0422	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	readme.gentoo-r1	22ae82e140bdd95d17a34fd5fd733190	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=08fcb4307b3e8090369aeb0809b6ab40
diff --git a/metadata/md5-cache/sci-chemistry/gromacs-9999 b/metadata/md5-cache/sci-chemistry/gromacs-9999
index 95e66e3ac406..962b4a1979c5 100644
--- a/metadata/md5-cache/sci-chemistry/gromacs-9999
+++ b/metadata/md5-cache/sci-chemistry/gromacs-9999
@@ -1,4 +1,4 @@
-BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_6? ( dev-lang/python:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( dev-lang/python:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] ) !sci-chemistry/gmxapi virtual/pkgconfig doc? ( app-doc/doxygen python_single_target_python3_6? ( dev-python/sphinx[python_targets_python3_6(-)] ) python_single_target_python3_7? ( dev-python/sphinx[python_targets_python3_7(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) dev-util/ninja >=dev-util/cmake-3.9.6 python_single_target_python3_6? ( dev-lang/python:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( dev-lang/python:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] ) python_single_target_python3_6? ( >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)] ) python_single_target_python3_7? ( >=dev-python/setuptools-42.0.2[python_targets_python3_7(-)] ) >=dev-vcs/git-1.8.2.1[curl]
+BDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_6? ( >=dev-lang/python-3.6.10:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( >=dev-lang/python-3.7.6:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] ) !sci-chemistry/gmxapi virtual/pkgconfig doc? ( app-doc/doxygen python_single_target_python3_6? ( dev-python/sphinx[python_targets_python3_6(-)] ) python_single_target_python3_7? ( dev-python/sphinx[python_targets_python3_7(-)] ) media-gfx/mscgen media-gfx/graphviz dev-texlive/texlive-latex dev-texlive/texlive-latexextra media-gfx/imagemagick ) dev-util/ninja >=dev-util/cmake-3.9.6 python_single_target_python3_6? ( >=dev-lang/python-3.6.10:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( >=dev-lang/python-3.7.6:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] ) python_single_target_python3_6? ( >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)] ) python_single_target_python3_7? ( >=dev-python/setuptools-42.0.2[python_targets_python3_7(-)] ) >=dev-vcs/git-1.8.2.1[curl]
 DEFINED_PHASES=compile configure install postinst prepare pretend setup test unpack
 DESCRIPTION=The ultimate molecular dynamics simulation package
 EAPI=7
@@ -6,9 +6,9 @@ HOMEPAGE=http://www.gromacs.org/
 IUSE=X blas cuda +doc -double-precision +fftw +gmxapi +gmxapi-legacy +hwloc lapack +lmfit mkl mpi +offensive opencl openmp +python +single-precision test +threads +tng cpu_flags_x86_sse2 cpu_flags_x86_sse4_1 cpu_flags_x86_fma4 cpu_flags_x86_avx cpu_flags_x86_avx2 python_single_target_python3_6 python_single_target_python3_7
 LICENSE=LGPL-2.1 UoI-NCSA !mkl? ( !fftw? ( BSD ) !blas? ( BSD ) !lapack? ( BSD ) ) cuda? ( LGPL-3 ) threads? ( BSD )
 PROPERTIES=live
-RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_6? ( dev-lang/python:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( dev-lang/python:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] ) !sci-chemistry/gmxapi python_single_target_python3_6? ( dev-lang/python:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( dev-lang/python:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] )
+RDEPEND=X? ( x11-libs/libX11 x11-libs/libSM x11-libs/libICE ) blas? ( virtual/blas ) cuda? ( >=dev-util/nvidia-cuda-toolkit-6.5.14 ) opencl? ( virtual/opencl ) fftw? ( sci-libs/fftw:3.0 ) hwloc? ( sys-apps/hwloc ) lapack? ( virtual/lapack ) lmfit? ( sci-libs/lmfit ) mkl? ( sci-libs/mkl ) mpi? ( virtual/mpi ) python_single_target_python3_6? ( >=dev-lang/python-3.6.10:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( >=dev-lang/python-3.7.6:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] ) !sci-chemistry/gmxapi python_single_target_python3_6? ( >=dev-lang/python-3.6.10:3.6 >=dev-lang/python-exec-2:=[python_targets_python3_6] ) python_single_target_python3_7? ( >=dev-lang/python-3.7.6:3.7 >=dev-lang/python-exec-2:=[python_targets_python3_7] )
 REQUIRED_USE=|| ( single-precision double-precision ) cuda? ( single-precision ) cuda? ( !opencl ) mkl? ( !blas !fftw !lapack ) ^^ ( python_single_target_python3_6 python_single_target_python3_7 ) ^^ ( python_single_target_python3_6 python_single_target_python3_7 )
 RESTRICT=!test? ( test )
 SLOT=0/9999
-_eclasses_=bash-completion-r1	47a7402d95930413ce25ba8d857339bb	cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	cuda	bb861e5221b7272ac90c2f12791c1e66	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	git-r3	86a0188f2ad9eb3d65e4d031ab8a0422	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	readme.gentoo-r1	22ae82e140bdd95d17a34fd5fd733190	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=bash-completion-r1	47a7402d95930413ce25ba8d857339bb	cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	cuda	bb861e5221b7272ac90c2f12791c1e66	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	git-r3	86a0188f2ad9eb3d65e4d031ab8a0422	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	readme.gentoo-r1	22ae82e140bdd95d17a34fd5fd733190	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=96ba8d07d1e0f1fa70eda3210b3bdb04
diff --git a/metadata/md5-cache/sci-chemistry/hollow-1.2-r1 b/metadata/md5-cache/sci-chemistry/hollow-1.2-r1
index 70bbc3a82ccd..55fb0f7864d7 100644
--- a/metadata/md5-cache/sci-chemistry/hollow-1.2-r1
+++ b/metadata/md5-cache/sci-chemistry/hollow-1.2-r1
@@ -1,14 +1,14 @@
 DEFINED_PHASES=install
-DEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] app-arch/unzip
+DEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] app-arch/unzip
 DESCRIPTION=Production of surface images of proteins
 EAPI=5
 HOMEPAGE=http://hollow.sourceforge.net/
 IUSE=python_targets_python2_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=GPL-3
-RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] sci-chemistry/pymol[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] sci-chemistry/pymol[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 REQUIRED_USE=|| ( python_targets_python2_7 )
 SLOT=0
 SRC_URI=http://hollow.sourceforge.net/hollow-1.2.zip
-_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
+_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
 _md5_=585a78404589d6da4fd5e45799219c86
diff --git a/metadata/md5-cache/sci-chemistry/mdtraj-1.9.1 b/metadata/md5-cache/sci-chemistry/mdtraj-1.9.1
index 01439cac4c32..70e7583a1cf2 100644
--- a/metadata/md5-cache/sci-chemistry/mdtraj-1.9.1
+++ b/metadata/md5-cache/sci-chemistry/mdtraj-1.9.1
@@ -1,15 +1,15 @@
 DEFINED_PHASES=compile configure install prepare test
-DEPEND=dev-python/setuptools[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-libs/scipy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/pandas[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/pytables[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/networkx[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] test? ( dev-python/nose[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] ) python_targets_python3_6? ( dev-lang/python:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
+DEPEND=dev-python/setuptools[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-libs/scipy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/pandas[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/pytables[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/networkx[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] test? ( dev-python/nose[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] ) python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
 DESCRIPTION=Read, write and analyze MD trajectories with only a few lines of Python code
 EAPI=6
 HOMEPAGE=http://mdtraj.org
 IUSE=test python_targets_python3_6
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=GPL-2
-RDEPEND=dev-python/setuptools[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-libs/scipy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/pandas[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/pytables[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/networkx[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] python_targets_python3_6? ( dev-lang/python:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
+RDEPEND=dev-python/setuptools[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-libs/scipy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/pandas[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/pytables[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/networkx[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
 REQUIRED_USE=|| ( python_targets_python3_6 )
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=mirror://pypi/m/mdtraj/mdtraj-1.9.1.tar.gz
-_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=d5c2def55b907191790ccfb305372914
diff --git a/metadata/md5-cache/sci-chemistry/modeller-9.20 b/metadata/md5-cache/sci-chemistry/modeller-9.20
index e9f14077acbd..631eb9e6709c 100644
--- a/metadata/md5-cache/sci-chemistry/modeller-9.20
+++ b/metadata/md5-cache/sci-chemistry/modeller-9.20
@@ -1,15 +1,15 @@
 DEFINED_PHASES=compile config configure install postinst postrm prepare setup test
-DEPEND=>=dev-lang/swig-1.3 python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] >=dev-python/setuptools-42.0.2[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+DEPEND=>=dev-lang/swig-1.3 python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] >=dev-python/setuptools-42.0.2[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 DESCRIPTION=Homology or comparative modeling of protein three-dimensional structures
 EAPI=6
 HOMEPAGE=https://salilab.org/modeller/
 IUSE=doc examples python_targets_python2_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=modeller
-RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 REQUIRED_USE=|| ( python_targets_python2_7 )
 RESTRICT=mirror
 SLOT=0
 SRC_URI=https://salilab.org/modeller/9.20/modeller-9.20.tar.gz
-_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	versionator	2352c3fc97241f6a02042773c8287748	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	versionator	2352c3fc97241f6a02042773c8287748	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=f358e2d41b8daba90ce8af54cc6f16c8
diff --git a/metadata/md5-cache/sci-chemistry/modeller-9.22 b/metadata/md5-cache/sci-chemistry/modeller-9.22
index a9fccbe3d5ba..e527ec01fd2c 100644
--- a/metadata/md5-cache/sci-chemistry/modeller-9.22
+++ b/metadata/md5-cache/sci-chemistry/modeller-9.22
@@ -1,4 +1,4 @@
-BDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] >=dev-python/setuptools-42.0.2[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+BDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] >=dev-python/setuptools-42.0.2[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 DEFINED_PHASES=compile config configure install postinst postrm prepare setup test
 DEPEND=>=dev-lang/swig-1.3
 DESCRIPTION=Homology or comparative modeling of protein three-dimensional structures
@@ -7,10 +7,10 @@ HOMEPAGE=https://salilab.org/modeller/
 IUSE=doc examples python_targets_python2_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=modeller
-RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 REQUIRED_USE=|| ( python_targets_python2_7 )
 RESTRICT=mirror
 SLOT=0
 SRC_URI=https://salilab.org/modeller/9.22/modeller-9.22.tar.gz
-_eclasses_=distutils-r1	577e2308f7b36e26062d464f59a5ee6c	eutils	fcb2aa98e1948b835b5ae66ca52868c5	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
+_eclasses_=distutils-r1	577e2308f7b36e26062d464f59a5ee6c	eutils	fcb2aa98e1948b835b5ae66ca52868c5	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
 _md5_=277c298ef034b8d8ceb197f117e062c9
diff --git a/metadata/md5-cache/sci-chemistry/molequeue-0.9.0 b/metadata/md5-cache/sci-chemistry/molequeue-0.9.0
index 4b7a83a19cb7..fd82853f871a 100644
--- a/metadata/md5-cache/sci-chemistry/molequeue-0.9.0
+++ b/metadata/md5-cache/sci-chemistry/molequeue-0.9.0
@@ -1,16 +1,16 @@
 BDEPEND=doc? ( app-doc/doxygen ) dev-util/ninja >=dev-util/cmake-3.9.6 test? ( !prefix? ( x11-base/xorg-server[xvfb] ) x11-apps/xhost )
 DEFINED_PHASES=compile configure install prepare setup test
-DEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) dev-qt/qtcore:5 dev-qt/qtgui:5 dev-qt/qtnetwork:5 dev-qt/qtwidgets:5 zeromq? ( net-libs/cppzmq:0= )
+DEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) dev-qt/qtcore:5 dev-qt/qtgui:5 dev-qt/qtnetwork:5 dev-qt/qtwidgets:5 zeromq? ( net-libs/cppzmq:0= )
 DESCRIPTION=Abstract, manage and coordinate execution of tasks
 EAPI=7
 HOMEPAGE=https://www.openchemistry.org/projects/molequeue/
 IUSE=+client doc server test +zeromq +python_single_target_python2_7 test
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=BSD
-RDEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) dev-qt/qtcore:5 dev-qt/qtgui:5 dev-qt/qtnetwork:5 dev-qt/qtwidgets:5 zeromq? ( net-libs/cppzmq:0= )
+RDEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) dev-qt/qtcore:5 dev-qt/qtgui:5 dev-qt/qtnetwork:5 dev-qt/qtwidgets:5 zeromq? ( net-libs/cppzmq:0= )
 REQUIRED_USE=^^ ( python_single_target_python2_7 ) server? ( client ) test? ( server )
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=https://github.com/OpenChemistry/molequeue/archive/0.9.0.tar.gz -> molequeue-0.9.0.tar.gz
-_eclasses_=cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	virtualx	e49dbce7ac14426e1155497476915307	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	virtualx	e49dbce7ac14426e1155497476915307	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=3ef65c2ea193f8263a6ea903ea0a4e0f
diff --git a/metadata/md5-cache/sci-chemistry/nmrdepaker-1.0-r3 b/metadata/md5-cache/sci-chemistry/nmrdepaker-1.0-r3
index 5be69bfeab45..ba54fbcdd8e9 100644
--- a/metadata/md5-cache/sci-chemistry/nmrdepaker-1.0-r3
+++ b/metadata/md5-cache/sci-chemistry/nmrdepaker-1.0-r3
@@ -1,4 +1,4 @@
-BDEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) python_single_target_python2_7? ( >=dev-python/setuptools-42.0.2[python_targets_python2_7(-)] )
+BDEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) python_single_target_python2_7? ( >=dev-python/setuptools-42.0.2[python_targets_python2_7(-)] )
 DEFINED_PHASES=compile configure install prepare setup test
 DEPEND=python_single_target_python2_7? ( || ( >=dev-python/matplotlib-python2-0.98.5[gtk2,python_targets_python2_7(-)] >=dev-python/matplotlib-0.98.5[gtk2,python_targets_python2_7(-)] ) || ( dev-python/numpy-python2[python_targets_python2_7(-)] >=dev-python/numpy-1.2[python_targets_python2_7(-)] ) >=dev-python/pygtk-2.12:2[python_targets_python2_7(-)] )
 DESCRIPTION=Program to perform NMR spectra 'De-Pake-ing' and moment calculation
@@ -7,9 +7,9 @@ HOMEPAGE=https://launchpad.net/nmrdepaker
 IUSE=+python_single_target_python2_7
 KEYWORDS=~amd64
 LICENSE=GPL-3+
-RDEPEND=python_single_target_python2_7? ( || ( >=dev-python/matplotlib-python2-0.98.5[gtk2,python_targets_python2_7(-)] >=dev-python/matplotlib-0.98.5[gtk2,python_targets_python2_7(-)] ) || ( dev-python/numpy-python2[python_targets_python2_7(-)] >=dev-python/numpy-1.2[python_targets_python2_7(-)] ) >=dev-python/pygtk-2.12:2[python_targets_python2_7(-)] ) python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] )
+RDEPEND=python_single_target_python2_7? ( || ( >=dev-python/matplotlib-python2-0.98.5[gtk2,python_targets_python2_7(-)] >=dev-python/matplotlib-0.98.5[gtk2,python_targets_python2_7(-)] ) || ( dev-python/numpy-python2[python_targets_python2_7(-)] >=dev-python/numpy-1.2[python_targets_python2_7(-)] ) >=dev-python/pygtk-2.12:2[python_targets_python2_7(-)] ) python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] )
 REQUIRED_USE=^^ ( python_single_target_python2_7 )
 SLOT=0
 SRC_URI=https://launchpad.net/nmrdepaker/1.0/1.0/+download/nmrdepaker-1.0.tar.gz
-_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
+_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
 _md5_=784aca4ac49a5fb71d51186de2b92bdb
diff --git a/metadata/md5-cache/sci-chemistry/nmrglue-0.5-r1 b/metadata/md5-cache/sci-chemistry/nmrglue-0.5-r1
index 24616829a922..0fb84cc5a747 100644
--- a/metadata/md5-cache/sci-chemistry/nmrglue-0.5-r1
+++ b/metadata/md5-cache/sci-chemistry/nmrglue-0.5-r1
@@ -1,15 +1,15 @@
 DEFINED_PHASES=compile configure install prepare test
-DEPEND=test? ( dev-python/matplotlib[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-libs/scipy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/nose[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] ) python_targets_python3_6? ( dev-lang/python:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
+DEPEND=test? ( dev-python/matplotlib[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-libs/scipy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/nose[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] ) python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
 DESCRIPTION=A module for working with NMR data in Python
 EAPI=5
 HOMEPAGE=https://nmrglue.com/
 IUSE=test python_targets_python3_6
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=BSD
-RDEPEND=dev-python/matplotlib[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-libs/scipy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] python_targets_python3_6? ( dev-lang/python:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
+RDEPEND=dev-python/matplotlib[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] dev-python/numpy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] sci-libs/scipy[python_targets_python3_6(-)?,-python_single_target_python3_6(-)] python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,-python_single_target_python3_6(-)]
 REQUIRED_USE=|| ( python_targets_python3_6 )
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=https://github.com/jjhelmus/nmrglue/releases/download/v0.5/nmrglue-0.5.tar.gz
-_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=ab2665c2ea9926fa516db763ec3d8fc1
diff --git a/metadata/md5-cache/sci-chemistry/openbabel-python-2.4.1-r1 b/metadata/md5-cache/sci-chemistry/openbabel-python-2.4.1-r1
index c61cb5420979..051e65a82fb4 100644
--- a/metadata/md5-cache/sci-chemistry/openbabel-python-2.4.1-r1
+++ b/metadata/md5-cache/sci-chemistry/openbabel-python-2.4.1-r1
@@ -1,14 +1,14 @@
 DEFINED_PHASES=compile configure install prepare test
-DEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) python_targets_python3_6? ( dev-lang/python:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,python_targets_python3_6(-)?,-python_single_target_python2_7(-),-python_single_target_python3_6(-)] ~sci-chemistry/openbabel-2.4.1 sys-libs/zlib >=dev-lang/swig-2 sys-devel/make >=dev-util/cmake-3.9.6
+DEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,python_targets_python3_6(-)?,-python_single_target_python2_7(-),-python_single_target_python3_6(-)] ~sci-chemistry/openbabel-2.4.1 sys-libs/zlib >=dev-lang/swig-2 sys-devel/make >=dev-util/cmake-3.9.6
 DESCRIPTION=Python bindings for OpenBabel (including Pybel)
 EAPI=6
 HOMEPAGE=http://openbabel.sourceforge.net/
 IUSE=python_targets_python2_7 python_targets_python3_6
 KEYWORDS=amd64 ~arm x86 ~amd64-linux ~x86-linux
 LICENSE=GPL-2
-RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) python_targets_python3_6? ( dev-lang/python:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,python_targets_python3_6(-)?,-python_single_target_python2_7(-),-python_single_target_python3_6(-)] ~sci-chemistry/openbabel-2.4.1 sys-libs/zlib
+RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,python_targets_python3_6(-)?,-python_single_target_python2_7(-),-python_single_target_python3_6(-)] ~sci-chemistry/openbabel-2.4.1 sys-libs/zlib
 REQUIRED_USE=|| ( python_targets_python2_7 python_targets_python3_6 )
 SLOT=0/5
 SRC_URI=mirror://sourceforge/openbabel/openbabel-2.4.1.tar.gz
-_eclasses_=cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	desktop	3b1f1d9a6b749c9ce2d5182877265b23	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=cmake-utils	be72eac95bd029ad1d81d5d656c3c83b	desktop	3b1f1d9a6b749c9ce2d5182877265b23	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	ninja-utils	132cbb376048d079b5a012f5467c4e7f	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=a640722436640dbabe7630cb44d12bb7
diff --git a/metadata/md5-cache/sci-chemistry/p3d-0.4.3-r1 b/metadata/md5-cache/sci-chemistry/p3d-0.4.3-r1
index 58fed6705ed7..59d2502387e0 100644
--- a/metadata/md5-cache/sci-chemistry/p3d-0.4.3-r1
+++ b/metadata/md5-cache/sci-chemistry/p3d-0.4.3-r1
@@ -1,14 +1,14 @@
 DEFINED_PHASES=compile configure install prepare test unpack
-DEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] >=dev-python/setuptools-42.0.2[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+DEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] >=dev-python/setuptools-42.0.2[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 DESCRIPTION=Python module for structural bioinformatics
 EAPI=6
 HOMEPAGE=http://p3d.fufezan.net/
 IUSE=examples python_targets_python2_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=GPL-3
-RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 REQUIRED_USE=|| ( python_targets_python2_7 )
 SLOT=0
 SRC_URI=https://nodeload.github.com/fu/p3d/tarball/0.4.3 -> p3d-0.4.3.tar.gz
-_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	vcs-snapshot	b1abf460a493fc59ebb25de0df3f09dd	versionator	2352c3fc97241f6a02042773c8287748	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	vcs-snapshot	b1abf460a493fc59ebb25de0df3f09dd	versionator	2352c3fc97241f6a02042773c8287748	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=9e3832010a5347eb6c9e4bba5441e9a5
diff --git a/metadata/md5-cache/sci-chemistry/p3d-9999 b/metadata/md5-cache/sci-chemistry/p3d-9999
index 15fc59c8de57..f17ed4b24a61 100644
--- a/metadata/md5-cache/sci-chemistry/p3d-9999
+++ b/metadata/md5-cache/sci-chemistry/p3d-9999
@@ -1,13 +1,13 @@
 DEFINED_PHASES=compile configure install prepare test unpack
-DEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] >=dev-python/setuptools-42.0.2[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] >=dev-vcs/git-1.8.2.1[curl]
+DEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] >=dev-python/setuptools-42.0.2[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] >=dev-vcs/git-1.8.2.1[curl]
 DESCRIPTION=Python module for structural bioinformatics
 EAPI=6
 HOMEPAGE=http://p3d.fufezan.net/
 IUSE=examples python_targets_python2_7
 LICENSE=GPL-3
 PROPERTIES=live
-RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 REQUIRED_USE=|| ( python_targets_python2_7 )
 SLOT=0
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diff --git a/metadata/md5-cache/sci-chemistry/pdb-tools-0.2.1-r1 b/metadata/md5-cache/sci-chemistry/pdb-tools-0.2.1-r1
index 212ce71439bb..eef020ba11e9 100644
--- a/metadata/md5-cache/sci-chemistry/pdb-tools-0.2.1-r1
+++ b/metadata/md5-cache/sci-chemistry/pdb-tools-0.2.1-r1
@@ -1,14 +1,14 @@
 DEFINED_PHASES=compile install prepare setup
-DEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) virtual/fortran
+DEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) virtual/fortran
 DESCRIPTION=Tools for manipulating and calculations on wwPDB macromolecule structure files
 EAPI=5
 HOMEPAGE=https://github.com/harmslab/pdbtools
 IUSE=+python_single_target_python2_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=GPL-3
-RDEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) virtual/fortran
+RDEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) virtual/fortran
 REQUIRED_USE=^^ ( python_single_target_python2_7 )
 SLOT=0
 SRC_URI=https://pdb-tools.googlecode.com/files/pdbTools_0.2.1.tar.gz
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diff --git a/metadata/md5-cache/sci-chemistry/pdb-tools-0.2.1-r2 b/metadata/md5-cache/sci-chemistry/pdb-tools-0.2.1-r2
index 70a6dccae0cf..4b67eb10778e 100644
--- a/metadata/md5-cache/sci-chemistry/pdb-tools-0.2.1-r2
+++ b/metadata/md5-cache/sci-chemistry/pdb-tools-0.2.1-r2
@@ -1,14 +1,14 @@
 DEFINED_PHASES=compile install prepare setup
-DEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) virtual/fortran
+DEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) virtual/fortran
 DESCRIPTION=Tools for manipulating and calculations on wwPDB macromolecule structure files
 EAPI=5
 HOMEPAGE=https://github.com/harmslab/pdbtools
 IUSE=+python_single_target_python2_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=GPL-3
-RDEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) virtual/fortran
+RDEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) virtual/fortran
 REQUIRED_USE=^^ ( python_single_target_python2_7 )
 SLOT=0
 SRC_URI=https://pdb-tools.googlecode.com/files/pdbTools_0.2.1.tar.gz
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+_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	fortran-2	1a8c9d0b2d30f756bae6be4e9b39e46b	ltprune	2729691420b6deeda2a90b1f1183fb55	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
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diff --git a/metadata/md5-cache/sci-chemistry/pdb2pqr-1.9.0-r3 b/metadata/md5-cache/sci-chemistry/pdb2pqr-1.9.0-r3
index 9e32654b0287..dfaf5f4dfe79 100644
--- a/metadata/md5-cache/sci-chemistry/pdb2pqr-1.9.0-r3
+++ b/metadata/md5-cache/sci-chemistry/pdb2pqr-1.9.0-r3
@@ -1,14 +1,14 @@
 DEFINED_PHASES=compile configure install prepare setup test
-DEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) python_single_target_python2_7? ( || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) sci-chemistry/openbabel-python[python_targets_python2_7(-)] opal? ( dev-python/zsi[python_targets_python2_7(-)] ) ) pdb2pka? ( sci-chemistry/apbs[python_single_target_python2_7(-)?,-mpi] ) dev-lang/swig:0 dev-util/scons[python_targets_python2_7] virtual/fortran
+DEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) python_single_target_python2_7? ( || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) sci-chemistry/openbabel-python[python_targets_python2_7(-)] opal? ( dev-python/zsi[python_targets_python2_7(-)] ) ) pdb2pka? ( sci-chemistry/apbs[python_single_target_python2_7(-)?,-mpi] ) dev-lang/swig:0 dev-util/scons[python_targets_python2_7] virtual/fortran
 DESCRIPTION=Automated pipeline for performing Poisson-Boltzmann electrostatics calculations
 EAPI=5
 HOMEPAGE=https://www.poissonboltzmann.org/
 IUSE=doc examples opal +pdb2pka +python_single_target_python2_7
 KEYWORDS=amd64 x86 ~amd64-linux ~x86-linux
 LICENSE=BSD
-RDEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) python_single_target_python2_7? ( || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) sci-chemistry/openbabel-python[python_targets_python2_7(-)] opal? ( dev-python/zsi[python_targets_python2_7(-)] ) ) pdb2pka? ( sci-chemistry/apbs[python_single_target_python2_7(-)?,-mpi] ) virtual/fortran
+RDEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) python_single_target_python2_7? ( || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) sci-chemistry/openbabel-python[python_targets_python2_7(-)] opal? ( dev-python/zsi[python_targets_python2_7(-)] ) ) pdb2pka? ( sci-chemistry/apbs[python_single_target_python2_7(-)?,-mpi] ) virtual/fortran
 REQUIRED_USE=^^ ( python_single_target_python2_7 )
 SLOT=0
 SRC_URI=https://github.com/Electrostatics/apbs-pdb2pqr/releases/download/pdb2pqr-1.9.0/pdb2pqr-src-1.9.0.tar.gz
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 _md5_=164d685691a3a1181130afc0942f1d1e
diff --git a/metadata/md5-cache/sci-chemistry/prodecomp-3.0-r3 b/metadata/md5-cache/sci-chemistry/prodecomp-3.0-r3
index 40c774391b68..75cd09f4f0e6 100644
--- a/metadata/md5-cache/sci-chemistry/prodecomp-3.0-r3
+++ b/metadata/md5-cache/sci-chemistry/prodecomp-3.0-r3
@@ -1,14 +1,14 @@
 DEFINED_PHASES=install setup
-DEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7[tk] >=dev-lang/python-exec-2:=[python_targets_python2_7] )
+DEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7[tk] >=dev-lang/python-exec-2:=[python_targets_python2_7] )
 DESCRIPTION=Decomposition-based analysis of NMR projections
 EAPI=5
 HOMEPAGE=http://www.lundberg.gu.se/nmr/software.php?program=PRODECOMP
 IUSE=examples +python_single_target_python2_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=GPL-2
-RDEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7[tk] >=dev-lang/python-exec-2:=[python_targets_python2_7] ) python_single_target_python2_7? ( || ( sci-libs/scipy-python2[python_targets_python2_7(-)] sci-libs/scipy[python_targets_python2_7(-)] ) )
+RDEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7[tk] >=dev-lang/python-exec-2:=[python_targets_python2_7] ) python_single_target_python2_7? ( || ( sci-libs/scipy-python2[python_targets_python2_7(-)] sci-libs/scipy[python_targets_python2_7(-)] ) )
 REQUIRED_USE=^^ ( python_single_target_python2_7 )
 SLOT=0
 SRC_URI=mirror://gentoo/prodecomp-3.0.tar.bz2
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 _md5_=57631c851f12fa821ecb7db673eeb431
diff --git a/metadata/md5-cache/sci-chemistry/propka-3.1_p140511 b/metadata/md5-cache/sci-chemistry/propka-3.1_p140511
index bfaddb2d5d0a..4b5d0241ed7a 100644
--- a/metadata/md5-cache/sci-chemistry/propka-3.1_p140511
+++ b/metadata/md5-cache/sci-chemistry/propka-3.1_p140511
@@ -1,15 +1,15 @@
 DEFINED_PHASES=compile configure install prepare test
-DEPEND=dev-python/setuptools[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] >=dev-python/setuptools-42.0.2[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+DEPEND=dev-python/setuptools[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] >=dev-python/setuptools-42.0.2[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 DESCRIPTION=pKa-value prediction of ionizable groups in protein and protein-ligand complexes
 EAPI=5
 HOMEPAGE=http://propka.ki.ku.dk/
 IUSE=python_targets_python2_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=all-rights-reserved
-RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 REQUIRED_USE=|| ( python_targets_python2_7 )
 RESTRICT=mirror bindist
 SLOT=0
 SRC_URI=https://dev.gentoo.org/~jlec/distfiles/propka-3.1_p140511.tar.xz
-_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=77a50416f48bdac3be53689262fbd770
diff --git a/metadata/md5-cache/sci-chemistry/pymol-2.3.0-r2 b/metadata/md5-cache/sci-chemistry/pymol-2.3.0-r2
index ddcf0672017a..bd5b84a4494d 100644
--- a/metadata/md5-cache/sci-chemistry/pymol-2.3.0-r2
+++ b/metadata/md5-cache/sci-chemistry/pymol-2.3.0-r2
@@ -1,4 +1,4 @@
-BDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] >=dev-python/setuptools-42.0.2[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+BDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] >=dev-python/setuptools-42.0.2[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 DEFINED_PHASES=compile configure install postinst postrm prepare test
 DEPEND=dev-libs/msgpack[cxx] dev-libs/mmtf-cpp || ( dev-python/numpy-python2[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] ) dev-python/pmw:py2[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] dev-python/pyopengl[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] dev-python/PyQt5[opengl,python_targets_python2_7(-)?,-python_single_target_python2_7(-)] media-libs/freetype:2 media-libs/glew:0= media-libs/glm media-libs/libpng:0= media-video/mpeg-tools sys-libs/zlib !sci-chemistry/pymol-apbs-plugin[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] web? ( !dev-python/webpy[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] )
 DESCRIPTION=A Python-extensible molecular graphics system
@@ -7,10 +7,10 @@ HOMEPAGE=https://www.pymol.org/
 IUSE=web python_targets_python2_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux ~x64-macos ~x86-macos
 LICENSE=PSF-2.2
-RDEPEND=dev-libs/msgpack[cxx] dev-libs/mmtf-cpp || ( dev-python/numpy-python2[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] ) dev-python/pmw:py2[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] dev-python/pyopengl[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] dev-python/PyQt5[opengl,python_targets_python2_7(-)?,-python_single_target_python2_7(-)] media-libs/freetype:2 media-libs/glew:0= media-libs/glm media-libs/libpng:0= media-video/mpeg-tools sys-libs/zlib !sci-chemistry/pymol-apbs-plugin[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] web? ( !dev-python/webpy[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] ) sci-chemistry/chemical-mime-data python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+RDEPEND=dev-libs/msgpack[cxx] dev-libs/mmtf-cpp || ( dev-python/numpy-python2[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] ) dev-python/pmw:py2[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] dev-python/pyopengl[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] dev-python/PyQt5[opengl,python_targets_python2_7(-)?,-python_single_target_python2_7(-)] media-libs/freetype:2 media-libs/glew:0= media-libs/glm media-libs/libpng:0= media-video/mpeg-tools sys-libs/zlib !sci-chemistry/pymol-apbs-plugin[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] web? ( !dev-python/webpy[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] ) sci-chemistry/chemical-mime-data python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 REQUIRED_USE=|| ( python_targets_python2_7 )
 RESTRICT=mirror
 SLOT=0
 SRC_URI=https://dev.gentoo.org/~jlec/distfiles/pymol-1.8.4.0.png.xz https://github.com/schrodinger/pymol-open-source/archive/v2.3.0.tar.gz -> pymol-2.3.0.tar.gz
-_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=2a58008ce405db59834b6aca5465b98c
diff --git a/metadata/md5-cache/sci-chemistry/pymol-2.3.0-r3 b/metadata/md5-cache/sci-chemistry/pymol-2.3.0-r3
index d88b3203581a..36c4ffc2c66c 100644
--- a/metadata/md5-cache/sci-chemistry/pymol-2.3.0-r3
+++ b/metadata/md5-cache/sci-chemistry/pymol-2.3.0-r3
@@ -1,4 +1,4 @@
-BDEPEND=python_targets_python3_6? ( dev-lang/python:3.6 ) python_targets_python3_7? ( dev-lang/python:3.7 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)]
+BDEPEND=python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) python_targets_python3_7? ( >=dev-lang/python-3.7.6:3.7 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] >=dev-python/setuptools-42.0.2[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)]
 DEFINED_PHASES=compile configure install postinst postrm prepare test
 DEPEND=dev-libs/msgpack[cxx] dev-libs/mmtf-cpp dev-python/pyopengl[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/PyQt5[opengl,python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/numpy[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] media-libs/freetype:2 media-libs/glew:0= media-libs/glm media-libs/libpng:0= media-video/mpeg-tools sys-libs/zlib
 DESCRIPTION=A Python-extensible molecular graphics system
@@ -7,10 +7,10 @@ HOMEPAGE=https://www.pymol.org/
 IUSE=web python_targets_python3_6 python_targets_python3_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux ~x64-macos ~x86-macos
 LICENSE=PSF-2.2
-RDEPEND=dev-libs/msgpack[cxx] dev-libs/mmtf-cpp dev-python/pyopengl[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/PyQt5[opengl,python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/numpy[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] media-libs/freetype:2 media-libs/glew:0= media-libs/glm media-libs/libpng:0= media-video/mpeg-tools sys-libs/zlib sci-chemistry/chemical-mime-data python_targets_python3_6? ( dev-lang/python:3.6 ) python_targets_python3_7? ( dev-lang/python:3.7 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)]
+RDEPEND=dev-libs/msgpack[cxx] dev-libs/mmtf-cpp dev-python/pyopengl[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/PyQt5[opengl,python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] dev-python/numpy[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)] media-libs/freetype:2 media-libs/glew:0= media-libs/glm media-libs/libpng:0= media-video/mpeg-tools sys-libs/zlib sci-chemistry/chemical-mime-data python_targets_python3_6? ( >=dev-lang/python-3.6.10:3.6 ) python_targets_python3_7? ( >=dev-lang/python-3.7.6:3.7 ) >=dev-lang/python-exec-2:=[python_targets_python3_6(-)?,python_targets_python3_7(-)?,-python_single_target_python3_6(-),-python_single_target_python3_7(-)]
 REQUIRED_USE=|| ( python_targets_python3_6 python_targets_python3_7 )
 RESTRICT=mirror
 SLOT=0
 SRC_URI=https://dev.gentoo.org/~jlec/distfiles/pymol-1.8.4.0.png.xz https://github.com/schrodinger/pymol-open-source/archive/v2.3.0.tar.gz -> pymol-2.3.0.tar.gz
-_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	distutils-r1	577e2308f7b36e26062d464f59a5ee6c	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	multiprocessing	cac3169468f893670dac3e7cb940e045	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=ec9eed0ed3baedbe1727b4d841c697ff
diff --git a/metadata/md5-cache/sci-chemistry/pymol-plugins-bni-tools-0.27 b/metadata/md5-cache/sci-chemistry/pymol-plugins-bni-tools-0.27
index a8b6e444d668..ad42790d0581 100644
--- a/metadata/md5-cache/sci-chemistry/pymol-plugins-bni-tools-0.27
+++ b/metadata/md5-cache/sci-chemistry/pymol-plugins-bni-tools-0.27
@@ -1,14 +1,14 @@
 DEFINED_PHASES=install
-DEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] app-arch/unzip
+DEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] app-arch/unzip
 DESCRIPTION=Gives Pymol additional functionalities and presets to the PyMOL GUI
 EAPI=5
 HOMEPAGE=http://bni-tools.sourceforge.net/
 IUSE=python_targets_python2_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=CNRI
-RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] sci-chemistry/pymol[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] sci-chemistry/pymol[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 REQUIRED_USE=|| ( python_targets_python2_7 )
 SLOT=0
 SRC_URI=mirror://sourceforge/bni-tools/bni-tools/bni-tools-0.27/bni-tools-027.zip
-_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	versionator	2352c3fc97241f6a02042773c8287748
+_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	versionator	2352c3fc97241f6a02042773c8287748
 _md5_=26e80f9cc26451b29a4f8ca04045008b
diff --git a/metadata/md5-cache/sci-chemistry/pymol-plugins-caver-2.1.2 b/metadata/md5-cache/sci-chemistry/pymol-plugins-caver-2.1.2
index 3ded91144495..1427871e93b9 100644
--- a/metadata/md5-cache/sci-chemistry/pymol-plugins-caver-2.1.2
+++ b/metadata/md5-cache/sci-chemistry/pymol-plugins-caver-2.1.2
@@ -1,15 +1,15 @@
 DEFINED_PHASES=install nofetch
-DEPEND=app-arch/unzip python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+DEPEND=app-arch/unzip python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 DESCRIPTION=Calculation of pathways of proteins from buried cavities to outside solvent
 EAPI=5
 HOMEPAGE=http://loschmidt.chemi.muni.cz/caver/
 IUSE=python_targets_python2_7 elibc_FreeBSD
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=CAVER
-RDEPEND=>=virtual/jre-1.6 sci-chemistry/pymol[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+RDEPEND=>=virtual/jre-1.6 sci-chemistry/pymol[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 REQUIRED_USE=|| ( python_targets_python2_7 )
 RESTRICT=bindist fetch
 SLOT=0
 SRC_URI=Caver2_1_2_pymol_plugin.zip
-_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	eapi7-ver	f9ec87e93172b25ce65a85303dc06964	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	java-utils-2	a055407af6fd37cf3f692ba73d2d2ba5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	versionator	2352c3fc97241f6a02042773c8287748
+_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	eapi7-ver	f9ec87e93172b25ce65a85303dc06964	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	java-utils-2	a055407af6fd37cf3f692ba73d2d2ba5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf	versionator	2352c3fc97241f6a02042773c8287748
 _md5_=1b9276d61c0fdf87a6dac3f8ccebc3f9
diff --git a/metadata/md5-cache/sci-chemistry/pymol-plugins-dssp-110430-r1 b/metadata/md5-cache/sci-chemistry/pymol-plugins-dssp-110430-r1
index ff45f9630d08..8d97fd77707b 100644
--- a/metadata/md5-cache/sci-chemistry/pymol-plugins-dssp-110430-r1
+++ b/metadata/md5-cache/sci-chemistry/pymol-plugins-dssp-110430-r1
@@ -1,14 +1,14 @@
 DEFINED_PHASES=install prepare
-DEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+DEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 DESCRIPTION=DSSP Plugin for PyMOL
 EAPI=5
 HOMEPAGE=http://www.biotec.tu-dresden.de/~hongboz/dssp_pymol/dssp_pymol.html
 IUSE=python_targets_python2_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=BSD pymol
-RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] sci-chemistry/dssp sci-biology/stride sci-chemistry/pymol[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] sci-chemistry/dssp sci-biology/stride sci-chemistry/pymol[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 REQUIRED_USE=|| ( python_targets_python2_7 )
 SLOT=0
 SRC_URI=https://dev.gentoo.org/~jlec/distfiles/pymol-plugins-dssp-110430.py.xz
-_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
+_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
 _md5_=79fddf7d3218a4a1abda0a907031f6c7
diff --git a/metadata/md5-cache/sci-chemistry/pymol-plugins-emovie-1.0.4 b/metadata/md5-cache/sci-chemistry/pymol-plugins-emovie-1.0.4
index d24247934547..368e30bb2c1e 100644
--- a/metadata/md5-cache/sci-chemistry/pymol-plugins-emovie-1.0.4
+++ b/metadata/md5-cache/sci-chemistry/pymol-plugins-emovie-1.0.4
@@ -6,9 +6,9 @@ HOMEPAGE=http://www.weizmann.ac.il/ISPC/eMovie.html
 IUSE=python_targets_python2_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=GPL-2
-RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] >sci-chemistry/pymol-0.99[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] >sci-chemistry/pymol-0.99[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 REQUIRED_USE=|| ( python_targets_python2_7 )
 SLOT=0
 SRC_URI=http://www.weizmann.ac.il/ISPC/eMovie_package.zip
-_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
+_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
 _md5_=d231aed6b9f8cdc7d9aaf28ef4cf322c
diff --git a/metadata/md5-cache/sci-chemistry/pymol-plugins-msms-100415-r1 b/metadata/md5-cache/sci-chemistry/pymol-plugins-msms-100415-r1
index eb9a44d3e94e..7b450cb339be 100644
--- a/metadata/md5-cache/sci-chemistry/pymol-plugins-msms-100415-r1
+++ b/metadata/md5-cache/sci-chemistry/pymol-plugins-msms-100415-r1
@@ -1,14 +1,14 @@
 DEFINED_PHASES=install prepare unpack
-DEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] sci-chemistry/msms-bin sci-chemistry/pymol[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+DEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] sci-chemistry/msms-bin sci-chemistry/pymol[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 DESCRIPTION=GUI for MSMS and displaying its results in PyMOL
 EAPI=5
 HOMEPAGE=http://www.biotec.tu-dresden.de/~hongboz/msms_pymol/msms_pymol.html
 IUSE=python_targets_python2_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=BSD pymol
-RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] sci-chemistry/msms-bin sci-chemistry/pymol[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] sci-chemistry/msms-bin sci-chemistry/pymol[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 REQUIRED_USE=|| ( python_targets_python2_7 )
 SLOT=0
 SRC_URI=http://www.biotec.tu-dresden.de/~hongboz/msms_pymol/pymol_script/msms_pymol.py -> pymol-plugins-msms-100415.py
-_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
+_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
 _md5_=b19ae1fbe95c97233447cb0fbefaded1
diff --git a/metadata/md5-cache/sci-chemistry/pymol-plugins-promol-3.0.2-r1 b/metadata/md5-cache/sci-chemistry/pymol-plugins-promol-3.0.2-r1
index 3e655a56378d..4196b0d59187 100644
--- a/metadata/md5-cache/sci-chemistry/pymol-plugins-promol-3.0.2-r1
+++ b/metadata/md5-cache/sci-chemistry/pymol-plugins-promol-3.0.2-r1
@@ -5,10 +5,10 @@ HOMEPAGE=http://www.rit.edu/cos/ezviz/ProMOL_dl.html
 IUSE=python_targets_python2_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux
 LICENSE=all-rights-reserved
-RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] dev-python/pmw:py2[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] sci-chemistry/pymol[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
+RDEPEND=python_targets_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 ) >=dev-lang/python-exec-2:=[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] dev-python/pmw:py2[python_targets_python2_7(-)?,-python_single_target_python2_7(-)] sci-chemistry/pymol[python_targets_python2_7(-)?,-python_single_target_python2_7(-)]
 REQUIRED_USE=|| ( python_targets_python2_7 )
 RESTRICT=mirror bindist
 SLOT=0
 SRC_URI=http://www.rit.edu/cos/ezviz/ProMOL.zip -> pymol-plugins-promol-3.0.2.zip
-_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
+_eclasses_=desktop	3b1f1d9a6b749c9ce2d5182877265b23	epatch	ed88001f77c6dd0d5f09e45c1a5b480e	estack	686eaab303305a908fd57b2fd7617800	eutils	fcb2aa98e1948b835b5ae66ca52868c5	ltprune	2729691420b6deeda2a90b1f1183fb55	multibuild	40fe59465edacd730c644ec2bc197809	multilib	1d91b03d42ab6308b5f4f6b598ed110e	preserve-libs	ef207dc62baddfddfd39a164d9797648	python-r1	8386b016a2b3bbefa88443fdaa898057	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	vcs-clean	2a0f74a496fa2b1552c4f3398258b7bf
 _md5_=7f72068dce413463b7f8fdf55cbac471
diff --git a/metadata/md5-cache/sci-chemistry/relax-4.0.0-r4 b/metadata/md5-cache/sci-chemistry/relax-4.0.0-r4
index c3c26d1d94fe..57df757d24e0 100644
--- a/metadata/md5-cache/sci-chemistry/relax-4.0.0-r4
+++ b/metadata/md5-cache/sci-chemistry/relax-4.0.0-r4
@@ -1,15 +1,15 @@
 DEFINED_PHASES=compile install prepare setup test
-DEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) python_single_target_python2_7? ( dev-python/Numdifftools[python_targets_python2_7(-)] || ( dev-python/matplotlib-python2[python_targets_python2_7(-)] dev-python/matplotlib[python_targets_python2_7(-)] ) || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) dev-python/wxpython:3.0[python_targets_python2_7(-)] sci-chemistry/pymol[python_targets_python2_7(-)] >=sci-libs/bmrblib-1.0.3[python_targets_python2_7(-)] >=sci-libs/minfx-1.0.11[python_targets_python2_7(-)] || ( sci-libs/scipy-python2[python_targets_python2_7(-)] sci-libs/scipy[python_targets_python2_7(-)] ) ) sci-chemistry/molmol sci-chemistry/vmd sci-visualization/grace sci-visualization/opendx x11-libs/wxGTK:3.0[X] media-gfx/pngcrush test? ( python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) python_single_target_python2_7? ( dev-python/Numdifftools[python_targets_python2_7(-)] || ( dev-python/matplotlib-python2[python_targets_python2_7(-)] dev-python/matplotlib[python_targets_python2_7(-)] ) || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) dev-python/wxpython:3.0[python_targets_python2_7(-)] sci-chemistry/pymol[python_targets_python2_7(-)] >=sci-libs/bmrblib-1.0.3[python_targets_python2_7(-)] >=sci-libs/minfx-1.0.11[python_targets_python2_7(-)] || ( sci-libs/scipy-python2[python_targets_python2_7(-)] sci-libs/scipy[python_targets_python2_7(-)] ) ) sci-chemistry/molmol sci-chemistry/vmd sci-visualization/grace sci-visualization/opendx x11-libs/wxGTK:3.0[X] ) python_single_target_python2_7? ( dev-util/scons[python_targets_python2_7(-)] ) python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) test? ( !prefix? ( x11-base/xorg-server[xvfb] ) x11-apps/xhost )
+DEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) python_single_target_python2_7? ( dev-python/Numdifftools[python_targets_python2_7(-)] || ( dev-python/matplotlib-python2[python_targets_python2_7(-)] dev-python/matplotlib[python_targets_python2_7(-)] ) || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) dev-python/wxpython:3.0[python_targets_python2_7(-)] sci-chemistry/pymol[python_targets_python2_7(-)] >=sci-libs/bmrblib-1.0.3[python_targets_python2_7(-)] >=sci-libs/minfx-1.0.11[python_targets_python2_7(-)] || ( sci-libs/scipy-python2[python_targets_python2_7(-)] sci-libs/scipy[python_targets_python2_7(-)] ) ) sci-chemistry/molmol sci-chemistry/vmd sci-visualization/grace sci-visualization/opendx x11-libs/wxGTK:3.0[X] media-gfx/pngcrush test? ( python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) python_single_target_python2_7? ( dev-python/Numdifftools[python_targets_python2_7(-)] || ( dev-python/matplotlib-python2[python_targets_python2_7(-)] dev-python/matplotlib[python_targets_python2_7(-)] ) || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) dev-python/wxpython:3.0[python_targets_python2_7(-)] sci-chemistry/pymol[python_targets_python2_7(-)] >=sci-libs/bmrblib-1.0.3[python_targets_python2_7(-)] >=sci-libs/minfx-1.0.11[python_targets_python2_7(-)] || ( sci-libs/scipy-python2[python_targets_python2_7(-)] sci-libs/scipy[python_targets_python2_7(-)] ) ) sci-chemistry/molmol sci-chemistry/vmd sci-visualization/grace sci-visualization/opendx x11-libs/wxGTK:3.0[X] ) python_single_target_python2_7? ( dev-util/scons[python_targets_python2_7(-)] ) python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) test? ( !prefix? ( x11-base/xorg-server[xvfb] ) x11-apps/xhost )
 DESCRIPTION=Molecular dynamics by NMR data analysis
 EAPI=5
 HOMEPAGE=https://www.nmr-relax.com/
 IUSE=test +python_single_target_python2_7 test
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=GPL-2
-RDEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) python_single_target_python2_7? ( dev-python/Numdifftools[python_targets_python2_7(-)] || ( dev-python/matplotlib-python2[python_targets_python2_7(-)] dev-python/matplotlib[python_targets_python2_7(-)] ) || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) dev-python/wxpython:3.0[python_targets_python2_7(-)] sci-chemistry/pymol[python_targets_python2_7(-)] >=sci-libs/bmrblib-1.0.3[python_targets_python2_7(-)] >=sci-libs/minfx-1.0.11[python_targets_python2_7(-)] || ( sci-libs/scipy-python2[python_targets_python2_7(-)] sci-libs/scipy[python_targets_python2_7(-)] ) ) sci-chemistry/molmol sci-chemistry/vmd sci-visualization/grace sci-visualization/opendx x11-libs/wxGTK:3.0[X]
+RDEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) python_single_target_python2_7? ( dev-python/Numdifftools[python_targets_python2_7(-)] || ( dev-python/matplotlib-python2[python_targets_python2_7(-)] dev-python/matplotlib[python_targets_python2_7(-)] ) || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) dev-python/wxpython:3.0[python_targets_python2_7(-)] sci-chemistry/pymol[python_targets_python2_7(-)] >=sci-libs/bmrblib-1.0.3[python_targets_python2_7(-)] >=sci-libs/minfx-1.0.11[python_targets_python2_7(-)] || ( sci-libs/scipy-python2[python_targets_python2_7(-)] sci-libs/scipy[python_targets_python2_7(-)] ) ) sci-chemistry/molmol sci-chemistry/vmd sci-visualization/grace sci-visualization/opendx x11-libs/wxGTK:3.0[X]
 REQUIRED_USE=^^ ( python_single_target_python2_7 )
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=http://download.gna.org/relax/relax-4.0.0.src.tar.bz2
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diff --git a/metadata/md5-cache/sci-chemistry/sparky-3.115-r2 b/metadata/md5-cache/sci-chemistry/sparky-3.115-r2
index a3d053f1912d..41d0b4fed383 100644
--- a/metadata/md5-cache/sci-chemistry/sparky-3.115-r2
+++ b/metadata/md5-cache/sci-chemistry/sparky-3.115-r2
@@ -1,15 +1,15 @@
 DEFINED_PHASES=compile install prepare setup
-DEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7[tk] >=dev-lang/python-exec-2:=[python_targets_python2_7] ) app-shells/tcsh dev-lang/tcl:0= dev-lang/tk:0=
+DEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7[tk] >=dev-lang/python-exec-2:=[python_targets_python2_7] ) app-shells/tcsh dev-lang/tcl:0= dev-lang/tk:0=
 DESCRIPTION=Graphical NMR assignment and integration program for large polymers
 EAPI=6
 HOMEPAGE=http://www.cgl.ucsf.edu/home/sparky/
 IUSE=examples +python_single_target_python2_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=sparky
-RDEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7[tk] >=dev-lang/python-exec-2:=[python_targets_python2_7] ) app-shells/tcsh dev-lang/tcl:0= dev-lang/tk:0=
+RDEPEND=python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7[tk] >=dev-lang/python-exec-2:=[python_targets_python2_7] ) app-shells/tcsh dev-lang/tcl:0= dev-lang/tk:0=
 REQUIRED_USE=^^ ( python_single_target_python2_7 )
 RESTRICT=mirror
 SLOT=0
 SRC_URI=http://www.cgl.ucsf.edu/home/sparky/distrib-3.115/sparky-source-3.115.tar.gz
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diff --git a/metadata/md5-cache/sci-chemistry/viewmol-2.4.1-r3 b/metadata/md5-cache/sci-chemistry/viewmol-2.4.1-r3
index 32f84fdf76a1..b219ffa30920 100644
--- a/metadata/md5-cache/sci-chemistry/viewmol-2.4.1-r3
+++ b/metadata/md5-cache/sci-chemistry/viewmol-2.4.1-r3
@@ -1,14 +1,14 @@
 DEFINED_PHASES=compile install prepare setup
-DEPEND=media-libs/libpng:0= media-libs/tiff:0 virtual/glu virtual/opengl x11-libs/libX11 x11-libs/libXi x11-libs/libXmu x11-libs/libXt x11-libs/motif:0 python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7[tk(-)] >=dev-lang/python-exec-2:=[python_targets_python2_7] ) x11-base/xorg-proto
+DEPEND=media-libs/libpng:0= media-libs/tiff:0 virtual/glu virtual/opengl x11-libs/libX11 x11-libs/libXi x11-libs/libXmu x11-libs/libXt x11-libs/motif:0 python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7[tk(-)] >=dev-lang/python-exec-2:=[python_targets_python2_7] ) x11-base/xorg-proto
 DESCRIPTION=Open-source graphical front end for computational chemistry programs
 EAPI=6
 HOMEPAGE=http://viewmol.sourceforge.net/
 IUSE=+python_single_target_python2_7
 KEYWORDS=~amd64 ~x86
 LICENSE=GPL-2
-RDEPEND=media-libs/libpng:0= media-libs/tiff:0 virtual/glu virtual/opengl x11-libs/libX11 x11-libs/libXi x11-libs/libXmu x11-libs/libXt x11-libs/motif:0 python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7[tk(-)] >=dev-lang/python-exec-2:=[python_targets_python2_7] )
+RDEPEND=media-libs/libpng:0= media-libs/tiff:0 virtual/glu virtual/opengl x11-libs/libX11 x11-libs/libXi x11-libs/libXmu x11-libs/libXt x11-libs/motif:0 python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7[tk(-)] >=dev-lang/python-exec-2:=[python_targets_python2_7] )
 REQUIRED_USE=^^ ( python_single_target_python2_7 )
 SLOT=0
 SRC_URI=mirror://sourceforge/viewmol/viewmol-2.4.1.src.tgz
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diff --git a/metadata/md5-cache/sci-chemistry/vmd-1.9.2 b/metadata/md5-cache/sci-chemistry/vmd-1.9.2
index 8a16065f40df..a9b26d5e34ad 100644
--- a/metadata/md5-cache/sci-chemistry/vmd-1.9.2
+++ b/metadata/md5-cache/sci-chemistry/vmd-1.9.2
@@ -1,15 +1,15 @@
 DEFINED_PHASES=compile configure install nofetch prepare setup
-DEPEND=>=dev-lang/tk-8.6.1 dev-lang/perl dev-libs/expat python_single_target_python2_7? ( || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) ) sci-libs/netcdf:0= virtual/opengl >=x11-libs/fltk-1.1.10-r2:1 x11-libs/libXft x11-libs/libXi python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) gromacs? ( >=sci-chemistry/gromacs-5.0.4-r1[tng] ) sqlite? ( dev-db/sqlite:3= ) tachyon? ( >=media-gfx/tachyon-0.99_beta6 ) xinerama? ( x11-libs/libXinerama ) virtual/pkgconfig dev-lang/swig
+DEPEND=>=dev-lang/tk-8.6.1 dev-lang/perl dev-libs/expat python_single_target_python2_7? ( || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) ) sci-libs/netcdf:0= virtual/opengl >=x11-libs/fltk-1.1.10-r2:1 x11-libs/libXft x11-libs/libXi python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) gromacs? ( >=sci-chemistry/gromacs-5.0.4-r1[tng] ) sqlite? ( dev-db/sqlite:3= ) tachyon? ( >=media-gfx/tachyon-0.99_beta6 ) xinerama? ( x11-libs/libXinerama ) virtual/pkgconfig dev-lang/swig
 DESCRIPTION=Visual Molecular Dynamics
 EAPI=5
 HOMEPAGE=http://www.ks.uiuc.edu/Research/vmd/
 IUSE=cuda gromacs msms povray sqlite tachyon xinerama +python_single_target_python2_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=vmd
-RDEPEND=>=dev-lang/tk-8.6.1 dev-lang/perl dev-libs/expat python_single_target_python2_7? ( || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) ) sci-libs/netcdf:0= virtual/opengl >=x11-libs/fltk-1.1.10-r2:1 x11-libs/libXft x11-libs/libXi python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) gromacs? ( >=sci-chemistry/gromacs-5.0.4-r1[tng] ) sqlite? ( dev-db/sqlite:3= ) tachyon? ( >=media-gfx/tachyon-0.99_beta6 ) xinerama? ( x11-libs/libXinerama ) sci-biology/stride sci-chemistry/surf x11-terms/xterm msms? ( sci-chemistry/msms-bin ) povray? ( media-gfx/povray )
+RDEPEND=>=dev-lang/tk-8.6.1 dev-lang/perl dev-libs/expat python_single_target_python2_7? ( || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) ) sci-libs/netcdf:0= virtual/opengl >=x11-libs/fltk-1.1.10-r2:1 x11-libs/libXft x11-libs/libXi python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) gromacs? ( >=sci-chemistry/gromacs-5.0.4-r1[tng] ) sqlite? ( dev-db/sqlite:3= ) tachyon? ( >=media-gfx/tachyon-0.99_beta6 ) xinerama? ( x11-libs/libXinerama ) sci-biology/stride sci-chemistry/surf x11-terms/xterm msms? ( sci-chemistry/msms-bin ) povray? ( media-gfx/povray )
 REQUIRED_USE=^^ ( python_single_target_python2_7 )
 RESTRICT=fetch
 SLOT=0
 SRC_URI=https://dev.gentoo.org/~jlec/distfiles/vmd-1.9.2-gentoo-patches.tar.xz vmd-1.9.2.src.tar.gz
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diff --git a/metadata/md5-cache/sci-chemistry/vmd-1.9.3 b/metadata/md5-cache/sci-chemistry/vmd-1.9.3
index f1bc46abb8b1..626dd4976320 100644
--- a/metadata/md5-cache/sci-chemistry/vmd-1.9.3
+++ b/metadata/md5-cache/sci-chemistry/vmd-1.9.3
@@ -1,15 +1,15 @@
 DEFINED_PHASES=compile configure install nofetch prepare setup
-DEPEND=>=dev-lang/tk-8.6.1 dev-lang/perl dev-libs/expat python_single_target_python2_7? ( || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) ) sci-libs/netcdf:0= virtual/opengl >=x11-libs/fltk-1.1.10-r2:1 x11-libs/libXft x11-libs/libXi python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) gromacs? ( >=sci-chemistry/gromacs-5.0.4-r1:0=[tng] ) sqlite? ( dev-db/sqlite:3= ) tachyon? ( >=media-gfx/tachyon-0.99_beta6 ) xinerama? ( x11-libs/libXinerama ) virtual/pkgconfig dev-lang/swig
+DEPEND=>=dev-lang/tk-8.6.1 dev-lang/perl dev-libs/expat python_single_target_python2_7? ( || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) ) sci-libs/netcdf:0= virtual/opengl >=x11-libs/fltk-1.1.10-r2:1 x11-libs/libXft x11-libs/libXi python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) gromacs? ( >=sci-chemistry/gromacs-5.0.4-r1:0=[tng] ) sqlite? ( dev-db/sqlite:3= ) tachyon? ( >=media-gfx/tachyon-0.99_beta6 ) xinerama? ( x11-libs/libXinerama ) virtual/pkgconfig dev-lang/swig
 DESCRIPTION=Visual Molecular Dynamics
 EAPI=5
 HOMEPAGE=http://www.ks.uiuc.edu/Research/vmd/
 IUSE=cuda gromacs msms povray sqlite tachyon xinerama +python_single_target_python2_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=vmd
-RDEPEND=>=dev-lang/tk-8.6.1 dev-lang/perl dev-libs/expat python_single_target_python2_7? ( || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) ) sci-libs/netcdf:0= virtual/opengl >=x11-libs/fltk-1.1.10-r2:1 x11-libs/libXft x11-libs/libXi python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) gromacs? ( >=sci-chemistry/gromacs-5.0.4-r1:0=[tng] ) sqlite? ( dev-db/sqlite:3= ) tachyon? ( >=media-gfx/tachyon-0.99_beta6 ) xinerama? ( x11-libs/libXinerama ) sci-biology/stride sci-chemistry/surf x11-terms/xterm msms? ( sci-chemistry/msms-bin ) povray? ( media-gfx/povray )
+RDEPEND=>=dev-lang/tk-8.6.1 dev-lang/perl dev-libs/expat python_single_target_python2_7? ( || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) ) sci-libs/netcdf:0= virtual/opengl >=x11-libs/fltk-1.1.10-r2:1 x11-libs/libXft x11-libs/libXi python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) gromacs? ( >=sci-chemistry/gromacs-5.0.4-r1:0=[tng] ) sqlite? ( dev-db/sqlite:3= ) tachyon? ( >=media-gfx/tachyon-0.99_beta6 ) xinerama? ( x11-libs/libXinerama ) sci-biology/stride sci-chemistry/surf x11-terms/xterm msms? ( sci-chemistry/msms-bin ) povray? ( media-gfx/povray )
 REQUIRED_USE=^^ ( python_single_target_python2_7 )
 RESTRICT=fetch
 SLOT=0
 SRC_URI=https://dev.gentoo.org/~jlec/distfiles/vmd-1.9.3-gentoo-patches.tar.xz vmd-1.9.3.src.tar
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diff --git a/metadata/md5-cache/sci-chemistry/vmd-1.9.3-r1 b/metadata/md5-cache/sci-chemistry/vmd-1.9.3-r1
index 742411d51d45..faee94897761 100644
--- a/metadata/md5-cache/sci-chemistry/vmd-1.9.3-r1
+++ b/metadata/md5-cache/sci-chemistry/vmd-1.9.3-r1
@@ -1,16 +1,16 @@
 BDEPEND=virtual/pkgconfig dev-lang/swig
 DEFINED_PHASES=compile configure install nofetch prepare setup
-DEPEND=>=dev-lang/tk-8.6.1:0= dev-lang/perl dev-libs/expat python_single_target_python2_7? ( || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) ) sci-libs/netcdf:0= virtual/opengl >=x11-libs/fltk-1.1.10-r2:1 x11-libs/libXft x11-libs/libXi python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) gromacs? ( >=sci-chemistry/gromacs-5.0.4-r1:0=[tng] ) sqlite? ( dev-db/sqlite:3= ) tachyon? ( >=media-gfx/tachyon-0.99_beta6 ) xinerama? ( x11-libs/libXinerama )
+DEPEND=>=dev-lang/tk-8.6.1:0= dev-lang/perl dev-libs/expat python_single_target_python2_7? ( || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) ) sci-libs/netcdf:0= virtual/opengl >=x11-libs/fltk-1.1.10-r2:1 x11-libs/libXft x11-libs/libXi python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) gromacs? ( >=sci-chemistry/gromacs-5.0.4-r1:0=[tng] ) sqlite? ( dev-db/sqlite:3= ) tachyon? ( >=media-gfx/tachyon-0.99_beta6 ) xinerama? ( x11-libs/libXinerama )
 DESCRIPTION=Visual Molecular Dynamics
 EAPI=7
 HOMEPAGE=http://www.ks.uiuc.edu/Research/vmd/
 IUSE=cuda gromacs msms povray sqlite tachyon xinerama +python_single_target_python2_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=vmd
-RDEPEND=>=dev-lang/tk-8.6.1:0= dev-lang/perl dev-libs/expat python_single_target_python2_7? ( || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) ) sci-libs/netcdf:0= virtual/opengl >=x11-libs/fltk-1.1.10-r2:1 x11-libs/libXft x11-libs/libXi python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) gromacs? ( >=sci-chemistry/gromacs-5.0.4-r1:0=[tng] ) sqlite? ( dev-db/sqlite:3= ) tachyon? ( >=media-gfx/tachyon-0.99_beta6 ) xinerama? ( x11-libs/libXinerama ) sci-biology/stride sci-chemistry/surf x11-terms/xterm msms? ( sci-chemistry/msms-bin ) povray? ( media-gfx/povray )
+RDEPEND=>=dev-lang/tk-8.6.1:0= dev-lang/perl dev-libs/expat python_single_target_python2_7? ( || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) ) sci-libs/netcdf:0= virtual/opengl >=x11-libs/fltk-1.1.10-r2:1 x11-libs/libXft x11-libs/libXi python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) gromacs? ( >=sci-chemistry/gromacs-5.0.4-r1:0=[tng] ) sqlite? ( dev-db/sqlite:3= ) tachyon? ( >=media-gfx/tachyon-0.99_beta6 ) xinerama? ( x11-libs/libXinerama ) sci-biology/stride sci-chemistry/surf x11-terms/xterm msms? ( sci-chemistry/msms-bin ) povray? ( media-gfx/povray )
 REQUIRED_USE=^^ ( python_single_target_python2_7 )
 RESTRICT=fetch
 SLOT=0
 SRC_URI=https://dev.gentoo.org/~jlec/distfiles/vmd-1.9.3-gentoo-patches.tar.xz vmd-1.9.3.src.tar
-_eclasses_=cuda	bb861e5221b7272ac90c2f12791c1e66	desktop	3b1f1d9a6b749c9ce2d5182877265b23	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	multilib	1d91b03d42ab6308b5f4f6b598ed110e	prefix	c2993e4c430c1ee24f278983d6189501	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
+_eclasses_=cuda	bb861e5221b7272ac90c2f12791c1e66	desktop	3b1f1d9a6b749c9ce2d5182877265b23	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	multilib	1d91b03d42ab6308b5f4f6b598ed110e	prefix	c2993e4c430c1ee24f278983d6189501	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c
 _md5_=bf88bc8b1ce8870a84f794ca5b17274f
diff --git a/metadata/md5-cache/sci-chemistry/vmd-1.9.3-r4 b/metadata/md5-cache/sci-chemistry/vmd-1.9.3-r4
index 372b7240b569..c9a546c48dc0 100644
--- a/metadata/md5-cache/sci-chemistry/vmd-1.9.3-r4
+++ b/metadata/md5-cache/sci-chemistry/vmd-1.9.3-r4
@@ -1,16 +1,16 @@
 BDEPEND=virtual/pkgconfig dev-lang/swig
 DEFINED_PHASES=compile configure install nofetch postinst postrm preinst prepare setup
-DEPEND=>=dev-lang/tk-8.6.1:0= dev-lang/perl dev-libs/expat python_single_target_python2_7? ( || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) ) sci-libs/netcdf:0= virtual/opengl >=x11-libs/fltk-1.1.10-r2:1 x11-libs/libXft x11-libs/libXi python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) gromacs? ( >=sci-chemistry/gromacs-5.0.4-r1:0=[tng] ) sqlite? ( dev-db/sqlite:3= ) tachyon? ( >=media-gfx/tachyon-0.99_beta6 ) xinerama? ( x11-libs/libXinerama ) dev-util/desktop-file-utils x11-misc/shared-mime-info
+DEPEND=>=dev-lang/tk-8.6.1:0= dev-lang/perl dev-libs/expat python_single_target_python2_7? ( || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) ) sci-libs/netcdf:0= virtual/opengl >=x11-libs/fltk-1.1.10-r2:1 x11-libs/libXft x11-libs/libXi python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) gromacs? ( >=sci-chemistry/gromacs-5.0.4-r1:0=[tng] ) sqlite? ( dev-db/sqlite:3= ) tachyon? ( >=media-gfx/tachyon-0.99_beta6 ) xinerama? ( x11-libs/libXinerama ) dev-util/desktop-file-utils x11-misc/shared-mime-info
 DESCRIPTION=Visual Molecular Dynamics
 EAPI=7
 HOMEPAGE=http://www.ks.uiuc.edu/Research/vmd/
 IUSE=cuda gromacs msms povray sqlite tachyon xinerama +python_single_target_python2_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=vmd
-RDEPEND=>=dev-lang/tk-8.6.1:0= dev-lang/perl dev-libs/expat python_single_target_python2_7? ( || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) ) sci-libs/netcdf:0= virtual/opengl >=x11-libs/fltk-1.1.10-r2:1 x11-libs/libXft x11-libs/libXi python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) gromacs? ( >=sci-chemistry/gromacs-5.0.4-r1:0=[tng] ) sqlite? ( dev-db/sqlite:3= ) tachyon? ( >=media-gfx/tachyon-0.99_beta6 ) xinerama? ( x11-libs/libXinerama ) sci-biology/stride sci-chemistry/chemical-mime-data sci-chemistry/surf x11-terms/xterm msms? ( sci-chemistry/msms-bin ) povray? ( media-gfx/povray )
+RDEPEND=>=dev-lang/tk-8.6.1:0= dev-lang/perl dev-libs/expat python_single_target_python2_7? ( || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) ) sci-libs/netcdf:0= virtual/opengl >=x11-libs/fltk-1.1.10-r2:1 x11-libs/libXft x11-libs/libXi python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) gromacs? ( >=sci-chemistry/gromacs-5.0.4-r1:0=[tng] ) sqlite? ( dev-db/sqlite:3= ) tachyon? ( >=media-gfx/tachyon-0.99_beta6 ) xinerama? ( x11-libs/libXinerama ) sci-biology/stride sci-chemistry/chemical-mime-data sci-chemistry/surf x11-terms/xterm msms? ( sci-chemistry/msms-bin ) povray? ( media-gfx/povray )
 REQUIRED_USE=^^ ( python_single_target_python2_7 )
 RESTRICT=fetch
 SLOT=0
 SRC_URI=https://dev.gentoo.org/~jlec/distfiles/vmd-1.9.3-gentoo-patches.tar.xz vmd-1.9.3.src.tar
-_eclasses_=cuda	bb861e5221b7272ac90c2f12791c1e66	desktop	3b1f1d9a6b749c9ce2d5182877265b23	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	multilib	1d91b03d42ab6308b5f4f6b598ed110e	prefix	c2993e4c430c1ee24f278983d6189501	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg	c7ba313ea1eaf266f95cc6235f7d6a07	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=cuda	bb861e5221b7272ac90c2f12791c1e66	desktop	3b1f1d9a6b749c9ce2d5182877265b23	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	multilib	1d91b03d42ab6308b5f4f6b598ed110e	prefix	c2993e4c430c1ee24f278983d6189501	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg	c7ba313ea1eaf266f95cc6235f7d6a07	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=59aeef3d458f760731a594367e214c61
diff --git a/metadata/md5-cache/sci-chemistry/vmd-1.9.3-r5 b/metadata/md5-cache/sci-chemistry/vmd-1.9.3-r5
index fca27b8b875e..30267c2ede86 100644
--- a/metadata/md5-cache/sci-chemistry/vmd-1.9.3-r5
+++ b/metadata/md5-cache/sci-chemistry/vmd-1.9.3-r5
@@ -1,16 +1,16 @@
 BDEPEND=virtual/pkgconfig dev-lang/swig
 DEFINED_PHASES=compile configure install nofetch postinst postrm preinst prepare setup
-DEPEND=>=dev-lang/tk-8.6.1:0= dev-lang/perl dev-libs/expat python_single_target_python2_7? ( || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) ) sci-libs/netcdf:0= virtual/opengl >=x11-libs/fltk-1.1.10-r2:1 x11-libs/libXft x11-libs/libXi python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) gromacs? ( >=sci-chemistry/gromacs-5.0.4-r1:0=[tng] ) sqlite? ( dev-db/sqlite:3= ) tachyon? ( >=media-gfx/tachyon-0.99_beta6 ) xinerama? ( x11-libs/libXinerama ) dev-util/desktop-file-utils x11-misc/shared-mime-info
+DEPEND=>=dev-lang/tk-8.6.1:0= dev-lang/perl dev-libs/expat python_single_target_python2_7? ( || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) ) sci-libs/netcdf:0= virtual/opengl >=x11-libs/fltk-1.1.10-r2:1 x11-libs/libXft x11-libs/libXi python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) gromacs? ( >=sci-chemistry/gromacs-5.0.4-r1:0=[tng] ) sqlite? ( dev-db/sqlite:3= ) tachyon? ( >=media-gfx/tachyon-0.99_beta6 ) xinerama? ( x11-libs/libXinerama ) dev-util/desktop-file-utils x11-misc/shared-mime-info
 DESCRIPTION=Visual Molecular Dynamics
 EAPI=7
 HOMEPAGE=http://www.ks.uiuc.edu/Research/vmd/
 IUSE=cuda gromacs msms povray sqlite tachyon xinerama +python_single_target_python2_7
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=vmd
-RDEPEND=>=dev-lang/tk-8.6.1:0= dev-lang/perl dev-libs/expat python_single_target_python2_7? ( || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) ) sci-libs/netcdf:0= virtual/opengl >=x11-libs/fltk-1.1.10-r2:1 x11-libs/libXft x11-libs/libXi python_single_target_python2_7? ( >=dev-lang/python-2.7.5-r2:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) gromacs? ( >=sci-chemistry/gromacs-5.0.4-r1:0=[tng] ) sqlite? ( dev-db/sqlite:3= ) tachyon? ( >=media-gfx/tachyon-0.99_beta6 ) xinerama? ( x11-libs/libXinerama ) sci-biology/stride sci-chemistry/chemical-mime-data sci-chemistry/surf x11-terms/xterm msms? ( sci-chemistry/msms-bin ) povray? ( media-gfx/povray )
+RDEPEND=>=dev-lang/tk-8.6.1:0= dev-lang/perl dev-libs/expat python_single_target_python2_7? ( || ( dev-python/numpy-python2[python_targets_python2_7(-)] dev-python/numpy[python_targets_python2_7(-)] ) ) sci-libs/netcdf:0= virtual/opengl >=x11-libs/fltk-1.1.10-r2:1 x11-libs/libXft x11-libs/libXi python_single_target_python2_7? ( >=dev-lang/python-2.7.17-r1:2.7 >=dev-lang/python-exec-2:=[python_targets_python2_7] ) cuda? ( >=dev-util/nvidia-cuda-toolkit-4.2.9-r1:= ) gromacs? ( >=sci-chemistry/gromacs-5.0.4-r1:0=[tng] ) sqlite? ( dev-db/sqlite:3= ) tachyon? ( >=media-gfx/tachyon-0.99_beta6 ) xinerama? ( x11-libs/libXinerama ) sci-biology/stride sci-chemistry/chemical-mime-data sci-chemistry/surf x11-terms/xterm msms? ( sci-chemistry/msms-bin ) povray? ( media-gfx/povray )
 REQUIRED_USE=^^ ( python_single_target_python2_7 )
 RESTRICT=fetch
 SLOT=0
 SRC_URI=https://dev.gentoo.org/~jlec/distfiles/vmd-1.9.3-gentoo-patches.tar.xz vmd-1.9.3.src.tar
-_eclasses_=cuda	bb861e5221b7272ac90c2f12791c1e66	desktop	3b1f1d9a6b749c9ce2d5182877265b23	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	multilib	1d91b03d42ab6308b5f4f6b598ed110e	prefix	c2993e4c430c1ee24f278983d6189501	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	e03f98555f2634bb9fb3160a8e30e3ec	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg	c7ba313ea1eaf266f95cc6235f7d6a07	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
+_eclasses_=cuda	bb861e5221b7272ac90c2f12791c1e66	desktop	3b1f1d9a6b749c9ce2d5182877265b23	eutils	fcb2aa98e1948b835b5ae66ca52868c5	flag-o-matic	42d97132740235ad4310cd60beb1992e	multilib	1d91b03d42ab6308b5f4f6b598ed110e	prefix	c2993e4c430c1ee24f278983d6189501	python-single-r1	151046e8d2ffc8cffc8329bbc50a686b	python-utils-r1	6f5996d2ae01e0c6f2869ed18f023239	toolchain-funcs	512eb3367f507ebaa1d1d43ab7d66e6c	xdg	c7ba313ea1eaf266f95cc6235f7d6a07	xdg-utils	ff2ff954e6b17929574eee4efc5152ba
 _md5_=33312b23eaf04a2d5f4b4303f115803a